| drug | Tazarotene |
| classification | Retinoid, Topical |
| pharmacokinetics | Tazarotene is a topical retinoid primarily absorbed through the skin. Systemic absorption is minimal but may occur with higher concentrations or prolonged use. Metabolism occurs primarily in the liver, and excretion is through urine and feces. |
| suggested dosage | Dosage varies by indication and skin condition. Consult a dermatologist for appropriate dosage and regimen. Generally, 0.05% or 0.1% cream or gel is applied once daily, gradually increasing to twice daily as tolerated. Start with small areas and avoid exceeding prescribed concentrations. |
| indications | Tazarotene is used topically to treat acne vulgaris, psoriasis, and other skin conditions with scaling and inflammation. It may be used for cutaneous T-cell lymphoma (CTCL) in specific cases. |
| safety in pregnancy | Pregnancy Category C. Tazarotene is generally not recommended during pregnancy. Consult a dermatologist to weigh potential benefits against risks to the developing fetus. Avoid use during pregnancy. |
| safety in breastfeeding | Not recommended during breastfeeding. Potential excretion into breast milk and risks to the nursing infant outweigh potential benefits. Consult a healthcare provider for alternatives. |
| side effects | | 1 | Skin irritation (redness, dryness, itching, burning, peeling) | | 2 | Skin inflammation (eczema-like reactions) | | 3 | Skin rash | | 4 | Hair loss (rare) | | 5 | Rare systemic side effects (headache, nausea; usually mild and temporary) | | 6 | Increased sun sensitivity |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to tazarotene or other retinoids | | 2 | Open or irritated skin lesions in the treatment area | | 3 | Active skin infections in the treatment area | | 4 | Breastfeeding |
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| interactions | Limited information on drug interactions; specific interactions depend on concomitant medications. Inform your doctor about all medications and supplements. |
| warnings and precautions | | 1 | Avoid prolonged or excessive sun exposure | | 2 | Apply a thin layer to the affected area only | | 3 | Use a broad-spectrum sunscreen (SPF 30 or higher) | | 4 | Do not use on broken or inflamed skin | | 5 | Monitor skin for irritation or reactions | | 6 | Discontinue use if severe side effects occur | | 7 | Avoid contact with eyes |
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| additional informations | Tazarotene is effective but use cautiously due to potential skin irritation. Consult a dermatologist for individual treatment plans. |
| patient profile | |
| disclaimer | This information is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional. |
