| name | Azelaic Acid |
| Classification | Keratolytic, comedolytic, anti-inflammatory agent |
| Pharmacokinetics | Azelaic acid is primarily absorbed topically and is slowly metabolized. Systemic absorption is minimal, making it generally safe. Excretion is primarily through the kidneys. There are no specific pharmacokinetic data based on age or weight in a general male population. |
| suggested dosage | | general | Typically applied topically once or twice daily, as per the prescription or product label instructions. | | patient specific | Please note that this information is not a substitute for medical advice. A healthcare professional can determine the appropriate dosage based on the patient's specific condition and needs. The provided information is for general knowledge only. |
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| indications | | 1 | Treatment of acne vulgaris, including inflammatory lesions and comedones (blackheads and whiteheads). | | 2 | Treatment of rosacea (in some cases). |
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| Safety in pregnancy | Limited data are available on the safety of azelaic acid during pregnancy. Consult with your healthcare provider to discuss the potential risks and benefits if you are pregnant or planning to become pregnant. |
| Safety in breastfeeding | Azelaic acid is considered to have a low risk of excretion into breast milk. However, consult your healthcare provider before using azelaic acid if you are breastfeeding. |
| side effects | | 1 | Skin irritation (e.g., redness, dryness, burning sensation), which is typically mild and transient. | | 2 | Skin discoloration (rare). | | 3 | Contact dermatitis (rare) | | 4 | Allergic reactions (rare) |
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| alternatives | | 1 | | | 2 | | drug | Salicylic Acid | | class | Keratolytic, comedolytic |
| | 3 | | drug | Tretinoin | | class | Vitamin A derivative, comedolytic, anti-inflammatory |
| | 4 | | drug | Sulfur | | class | Comedolytic, anti-inflammatory |
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| contraindications | | 1 | Known hypersensitivity to azelaic acid or any of its components. | | 2 | Use of the drug on open wounds or broken skin |
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| interactions | Limited interactions reported. No specific interactions are known based on age or weight. Consult with your physician if you are taking any other medications. |
| warnings and precautions | | 1 | Start with a low frequency or concentration and gradually increase as tolerated. | | 2 | Discontinue use if irritation worsens or if signs of allergy appear. | | 3 | Avoid prolonged sun exposure while using azelaic acid, as it may increase skin sensitivity. | | 4 | Apply a thin layer and avoid contact with eyes. |
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| additional informations | | important notes | This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional for personalized advice and treatment. |
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