| name | Ivermectin |
| Classification | Antiparasitic, Antiviral (limited efficacy) |
| Pharmacokinetics | Ivermectin is well absorbed orally, with peak plasma concentrations typically observed within 2-8 hours. It is highly protein-bound, primarily to albumin. Metabolism is primarily via the liver, and elimination is primarily via the feces. The half-life varies depending on the specific indication and formulation. |
| suggested dosage | Dosage varies significantly depending on the indication and patient factors. It is crucial to consult with a physician for specific guidance. Self-treating with ivermectin based on internet information is dangerous and should be avoided. |
| indications | | 1 | Onchocerciasis (river blindness) | | 2 | Strongyloidiasis | | 3 | Lymphatic filariasis | | 4 | Other parasitic infections (e.g., scabies, head lice) | | 5 | COVID-19 (limited and controversial evidence, should not be used for this) | | 6 | Severe COVID-19 |
|
| Safety in pregnancy | Limited data exists on the safety of ivermectin during pregnancy. Consult with a healthcare professional before using. |
| Safety in breastfeeding | Limited data exists on the safety of ivermectin during breastfeeding. Consult with a healthcare professional before using. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal pain | | 5 | Headache | | 6 | Fatigue | | 7 | Dizziness | | 8 | Skin rash | | 9 | Pruritus (itching) | | 10 | Constipation | | 11 | Elevated Liver Enzymes (rare) |
|
| alternatives | | 1 | | | 2 | | drug | Albendazole | | class | Antihelmintic |
| | 3 | | drug | Permethrin | | class | Antiparasitic |
| | 4 | | drug | Pyrantel Pamoate | | class | Antihelmintic |
|
|
| contraindications | | 1 | Known hypersensitivity or allergy to ivermectin | | 2 | Severe liver disease | | 3 | Pre-existing cardiovascular conditions in certain instances |
|
| interactions | Ivermectin can interact with several medications, including certain drugs affecting the liver or clotting factors. Always inform your doctor of all medications you are taking. |
| warnings and precautions | | 1 | Do not use ivermectin for self-treating any conditions. Consult a doctor. | | 2 | Careful monitoring of liver function is necessary during prolonged use or high doses. | | 3 | Individual responses to ivermectin can vary. Be aware of potential side effects. | | 4 | Ivermectin's effectiveness against COVID-19 is not well-established and is controversial. | | 5 | Avoid using this medication outside of a medically supervised context without a clear diagnosis. |
|
| additional informations | | 1 | Ivermectin is available in various formulations, including oral tablets, topical ointments and creams for certain conditions. Always use as directed by your doctor. | | 2 | Dosage and duration of treatment will vary according to the indication and patient's specific needs. | | 3 | Consult your doctor for advice on possible side effects and suitable dosing strategies for this particular patient. |
|
| patient specific notes | Patient age (25) and weight (70 kg) are not directly relevant to general dosage. Dosage must be determined for the specific condition for which ivermectin is being considered, and individual factors must be carefully evaluated with a physician. |
