| drug name | Tazarotene |
| classification | Topical retinoid |
| pharmacokinetics | Tazarotene is primarily absorbed and metabolized locally in the skin. Small amounts may be systemically absorbed, but systemic effects are generally minimal. Metabolism occurs primarily in the liver via the cytochrome P450 system. Specific pharmacokinetic profiles can vary based on formulation and individual patient factors. |
| suggested dosage | Dosage and frequency depend on the specific condition being treated. Generally, apply a thin layer once or twice daily to affected areas. Always follow the specific instructions provided by a healthcare professional. |
| indications | Tazarotene is primarily used for acne vulgaris and psoriasis. It may also be used for other skin conditions, such as seborrheic dermatitis and other inflammatory skin conditions, by promoting cell turnover and reducing inflammation. |
| safety in pregnancy | Tazarotene is not recommended during pregnancy due to potential risks to the developing fetus. Pregnant or potentially pregnant women should not use this medication without consulting a physician. |
| safety in breastfeeding | Tazarotene use during breastfeeding is not recommended due to unknown potential effects on the infant. Consult a healthcare professional before using topical medications while breastfeeding. |
| side effects | | 1 | Skin irritation (redness, dryness, scaling, burning, itching) | | 2 | Skin inflammation | | 3 | Excessive dryness or peeling | | 4 | Skin reactions (e.g., allergic contact dermatitis) | | 5 | Acne-like lesions | | 6 | Hair follicle inflammation |
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| alternatives | | 1 | | alternative name | Adapalene | | notes | Another topical retinoid with similar effects and potential reduced side effects in some individuals. |
| | 2 | | alternative name | Retinoic acid | | notes | A different form of retinoid available topically and orally. Use varies with skin condition severity; may have different side effect profiles. |
| | 3 | | | 4 | | alternative name | Tretinoin | | notes | A common topical retinoid, sometimes preferred for certain skin types or conditions. |
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| contraindications | | 1 | Known hypersensitivity to tazarotene or other retinoids | | 2 | Active skin infections or wounds at the application site | | 3 | Severe skin conditions requiring systemic treatment |
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| interactions | | 1 | Possible interactions with other topical medications. Consult a healthcare professional for potential interactions based on the patient's complete medication list. |
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| warnings and precautions | | 1 | Patients with sensitive skin may experience more side effects. | | 2 | Apply a thin layer and avoid contact with eyes and mucous membranes. | | 3 | Monitor skin reactions closely; discontinue use if significant irritation or hypersensitivity occurs. | | 4 | Do not use on broken skin. | | 5 | Tazarotene may increase skin sensitivity to sunlight. Use sunscreen and avoid prolonged sun exposure. |
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| additional information | Tazarotene is sometimes used with other acne treatments or in a stepwise approach. Treatment plans are tailored to individual patients based on the condition's type and severity. Consult a healthcare provider or dermatologist for concerns or questions. |
| patient profile | |
