name | Aspirin |
classification | Nonsteroidal Anti-inflammatory Drug (NSAID) |
pharmacokinetics | Aspirin is rapidly absorbed from the gastrointestinal tract. Maximum plasma concentrations are typically achieved within 30 minutes to 2 hours of oral administration. It is metabolized primarily in the liver. Elimination half-life varies depending on the dose and individual factors. Renal excretion is the primary route of elimination. |
dosage | adult | typical | 81 mg to 325 mg, as needed, or as directed by a physician | note | Specific dosages vary based on the condition being treated. Consult a healthcare professional for appropriate recommendations. |
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indications | 1 | Pain relief | 2 | Fever reduction | 3 | Reduction of risk of myocardial infarction and stroke | 4 | Treatment of certain inflammatory conditions (e.g., arthritis) |
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safety in pregnancy | Aspirin use in pregnancy is generally avoided unless absolutely necessary and under the direct supervision of a physician. Potential risks to the developing fetus should be weighed against the benefits of use. Aspirin use in the latter stages of pregnancy may be associated with complications at delivery. Consult your doctor. |
safety in breastfeeding | Aspirin may pass into breast milk. Use cautiously, if at all, and consult a physician before use if breastfeeding. Potential risks to the infant should be carefully evaluated by the physician. |
side effects | 1 | Gastrointestinal upset (e.g., nausea, heartburn, abdominal pain, stomach ulcers) | 2 | Bleeding risks | 3 | Allergic reactions (e.g., hives, rash, difficulty breathing) | 4 | Tinnitus (ringing in the ears) | 5 | Reye's syndrome (especially in children and adolescents) |
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alternatives | |
contraindications | 1 | History of aspirin allergy or hypersensitivity | 2 | Active gastrointestinal bleeding or ulceration | 3 | Certain bleeding disorders | 4 | Recent or planned surgery with significant bleeding risk |
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interactions | 1 | Other NSAIDs | 2 | Blood thinners (e.g., warfarin) | 3 | Corticosteroids | 4 | Certain medications for heart conditions | 5 | Some medications for cancer treatment | 6 | Alcohol |
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warnings and precautions | 1 | Do not use if allergic to aspirin or similar medications. | 2 | Caution with kidney or liver dysfunction. | 3 | Be aware of potential bleeding complications, especially when taking other medications increasing bleeding risk. | 4 | Avoid alcohol while taking aspirin, as it can exacerbate gastrointestinal side effects. |
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additional information | Consult a healthcare professional for appropriate use, dosage, and recommendations, especially for chronic or long-term use, or use with other medications. |
manufacturer details | 1 | manufacturer | Bayer | product name | Aspirin |
| 2 | manufacturer | Bristol-Myers Squibb | product name | Aspirin |
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