name | Acetaminophen |
Classification | Non-opioid analgesic and antipyretic |
Pharmacokinetics | Acetaminophen is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are usually reached within 30-60 minutes after oral administration. It is primarily metabolized in the liver. The metabolites are largely excreted in the urine. |
suggested dosage | adult general | 650-1000 mg every 4-6 hours, as needed for pain or fever. Maximum daily dose is 4 grams. | specific indications | Dosage may vary based on specific indication and individual patient factors. Always consult with a doctor or pharmacist before adjusting dosage or administering to a patient for the first time or for pre-existing conditions. |
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indications | Acetaminophen is primarily used to relieve mild to moderate pain, such as headaches, muscle aches, and toothaches, and to reduce fever. |
Safety in pregnancy | Acetaminophen is generally considered safe to use during pregnancy, especially in the short term. However, careful consideration of potential risks and benefits is crucial with long-term or high-dose use, especially during the third trimester. Consult a doctor before using. |
Safety in breastfeeding | Acetaminophen is considered generally safe for use while breastfeeding, as small amounts are excreted in breast milk. However, it is important to keep track of dosage and the amount taken should not exceed the indicated daily dosage. Consult a doctor before using. |
side effects | 1 | Nausea | 2 | Vomiting | 3 | Diarrhea | 4 | Loss of appetite | 5 | Rarely, liver damage is possible, particularly with high doses or prolonged use. | 6 | Allergic reactions (rash, itching, difficulty breathing) |
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alternatives | |
contraindications | 1 | Known hypersensitivity to acetaminophen | 2 | Severe liver disease | 3 | Certain rare genetic conditions affecting liver metabolism | 4 | Alcohol use disorders, particularly heavy drinking. Acetaminophen may interact with and exacerbate risks of liver damage. |
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interactions | 1 | Alcohol: | 2 | Can increase the risk of liver damage when used with alcohol. Avoid consuming alcohol while taking acetaminophen. | 3 | Warfarin: | 4 | May increase the risk of bleeding. Monitor for signs of bleeding when using both drugs. | 5 | Other medications: | 6 | Acetaminophen can interact with other medications; careful consideration should be given when combining. |
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warnings and precautions | 1 | Do not exceed recommended dosage. | 2 | Monitor for signs of liver problems. Symptoms may include fatigue, nausea, vomiting, or loss of appetite. | 3 | If experiencing any unusual symptoms consult with your doctor immediately. | 4 | Careful use for patients with pre-existing kidney or liver conditions. | 5 | Be aware of potential interactions with other medications or supplements. |
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additional informations | 1 | Acetaminophen can be used in combination with other medicines. A healthcare provider will be able to tailor a treatment regimen that is right for you. | 2 | Take acetaminophen as directed by your doctor. | 3 | Always inform your physician about all other medications, including over-the-counter drugs or supplements, you are currently taking. |
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patient details | age | 25 years | weight | 70 kg | gender | male |
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