| drug | Ibuprofen |
| classification | Nonsteroidal anti-inflammatory drug (NSAID) |
| pharmacokinetics | Ibuprofen is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are typically reached within 1-2 hours. It is extensively bound to plasma proteins. Elimination is primarily through the kidneys, with a half-life of approximately 2 hours. Metabolism occurs primarily in the liver. |
| suggested dosage | | adult | | oral | | 1 | | dosage | 200-400mg every 4-6 hours as needed | | note | For mild to moderate pain and inflammation. Adjust according to severity of symptoms and individual response. Do not exceed 3200mg in 24 hours |
| | 2 | | dosage | 600-800 mg every 8 hours | | note | May be used for more severe pain and inflammation |
|
|
| | note | Dosage should be adjusted based on individual patient response and medical condition. Always follow the instructions on the medication label. Consult a healthcare professional for specific dosage recommendations. |
|
| indications | | 1 | Mild to moderate pain (headache, toothache, muscle aches) | | 2 | Fever | | 3 | Inflammation (arthritis, musculoskeletal pain) | | 4 | Symptomatic relief of menstrual cramps |
|
| safety in pregnancy | Ibuprofen should be used with caution during pregnancy, especially in the third trimester. Potential risks to the fetus need to be considered. Consult with a doctor before use. |
| safety in breastfeeding | Ibuprofen is generally considered compatible with breastfeeding, but there are potential risks. The drug may pass into breast milk in low levels. Consult a healthcare professional before use to evaluate the potential benefits and risks. |
| side effects | | 1 | Gastrointestinal upset (nausea, vomiting, heartburn, abdominal pain, diarrhea) | | 2 | Headache | | 3 | Dizziness | | 4 | Rash | | 5 | Kidney problems (in high doses or with pre-existing kidney conditions) | | 6 | Bleeding risk | | 7 | Fluid retention |
|
| alternatives | |
| contraindications | | 1 | History of hypersensitivity to ibuprofen or other NSAIDs | | 2 | Active peptic ulcer disease | | 3 | Severe heart failure | | 4 | Bleeding disorders | | 5 | Recent history of major surgery or trauma | | 6 | History of asthma, rhinitis, or urticaria triggered by NSAIDs (aspirin sensitivity) |
|
| interactions | | 1 | Other NSAIDs | | 2 | Blood thinners (anticoagulants) | | 3 | Corticosteroids | | 4 | Diuretics | | 5 | Lithium | | 6 | Certain medications for high blood pressure | | 7 | Other medications with gastrointestinal side effects |
|
| warnings and precautions | | 1 | Use cautiously in patients with liver or kidney disease | | 2 | Avoid concurrent use with alcohol | | 3 | Monitor for signs of bleeding or gastrointestinal problems | | 4 | Inform doctor about any pre-existing conditions (e.g., heart disease, diabetes, high blood pressure) before starting ibuprofen use | | 5 | Do not use in patients with severe allergies to aspirin or other NSAIDs without a physician's supervision. | | 6 | May worsen pre-existing heart failure |
|
| additional informations | | 1 | Avoid use if taking other medications containing NSAIDs, unless specifically instructed by a healthcare professional | | 2 | Store in a cool, dry place, away from direct sunlight | | 3 | Never exceed the recommended dosage | | 4 | Note that individual responses to ibuprofen can vary. Monitor for any adverse effects and promptly contact your doctor if needed. | | 5 | This information is for general knowledge and does not constitute medical advice. Consult a physician for personalized advice regarding ibuprofen use. |
|
| patient details | |
