| drug | Naproxen |
| classification | Nonsteroidal anti-inflammatory drug (NSAID) |
| pharmacokinetics | | absorption | Rapidly absorbed from the gastrointestinal tract. | | distribution | Distributes throughout the body, including the tissues and organs. | | metabolism | Primarily metabolized in the liver. | | excretion | Excreted primarily in the urine. |
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| suggested dosage | | adults | | general | 250 mg to 500 mg every 6 to 8 hours as needed for pain or inflammation. | | specific conditions | Dosage may vary depending on individual needs and severity of condition. Consult a physician for specific dosage instructions. | | weight considerations | While weight generally isn't a primary dosage factor for naproxen, a physician may adjust based on individual circumstances, renal function, etc. |
| | note | Dosage should be determined by a healthcare professional, considering the patient's specific condition and other medications they may be taking. Never self-medicate. |
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| indications | | 1 | Pain relief (e.g., headache, muscle aches, back pain) | | 2 | Reduction of inflammation (e.g., arthritis, menstrual cramps) | | 3 | Treatment of fever |
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| safety in pregnancy | | category | Category C. Not recommended for routine use during pregnancy, especially in the later stages. Use only when the potential benefit outweighs the potential risk. | | additional notes | Consult with a healthcare professional for detailed considerations in any pregnancy or potential pregnancy. |
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| safety in breastfeeding | | potential effects | Naproxen is excreted into breast milk. May have adverse effects on the infant. Consult with a healthcare professional regarding potential benefits and risks. | | additional notes | Frequent monitoring of infant and use of the lowest effective dose may be necessary. |
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| side effects | | 1 | Gastrointestinal distress (e.g., heartburn, nausea, vomiting, diarrhea) | | 2 | Headache | | 3 | Dizziness | | 4 | Rash | | 5 | Kidney problems (rare, but serious) | | 6 | Bleeding (especially with other medications that increase bleeding risks) | | 7 | Stomach ulcers | | 8 | High blood pressure | | 9 | Serious allergic reactions (rare but potentially fatal). |
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| alternatives | |
| contraindications | | 1 | History of allergic reactions to NSAIDs | | 2 | Active peptic ulcers or gastrointestinal bleeding | | 3 | Severe heart failure | | 4 | Kidney disease | | 5 | Bleeding disorders | | 6 | Recent history of stroke or heart attack |
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| interactions | | 1 | Other NSAIDs | | 2 | Blood thinners | | 3 | Corticosteroids | | 4 | Certain medications for diabetes | | 5 | Certain diuretics | | 6 | Lithium | | 7 | Potassium-sparing diuretics | | 8 | Anti-platelet agents |
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| warnings and precautions | | 1 | Avoid use in patients with a history of asthma or other respiratory problems | | 2 | Monitor kidney function closely in patients at risk (e.g., those with pre-existing kidney disease or who are dehydrated) | | 3 | Use with caution in patients with hypertension or a history of heart disease. | | 4 | Consider using the lowest effective dose possible for the shortest duration possible | | 5 | Monitor for signs of bleeding or gastrointestinal complications |
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| additional informations | | patient age and weight | | considerations | Age and weight may influence dosage and treatment decisions, and should be factored into treatment plans by a healthcare provider, in accordance with the patient's specific condition. |
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