| name | Senna |
| Classification | Laxative (Stimulant) |
| Pharmacokinetics | Senna is primarily absorbed in the small intestine and exerts its laxative effect by stimulating peristalsis in the large intestine. The active compounds in senna are glycosides (e.g., sennosides). The exact mechanism of action is not fully understood, but involves the binding of the glycosides to specific receptors in the intestinal wall, triggering an increased movement of fluids and electrolytes into the intestinal tract. Excretion occurs primarily in the feces. |
| suggested dosage | | adult | Dosage depends on the formulation (e.g., senna tablets, senna syrup) and the specific product. Consult the product information leaflet for detailed information. Typical adult doses range from 7.5 mg to 15 mg of sennosides daily. Do not exceed the maximum dose or use the product for extended periods without consulting a physician. | | notes | Specific doses must be tailored to individual needs and the severity of constipation. |
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| indications | Senna is indicated for temporary relief of occasional constipation. It should not be used as a long-term treatment for chronic constipation without medical supervision. |
| Safety in pregnancy | Limited data are available on the safety of senna use during pregnancy. Some studies suggest that there may be some potential risks, including stimulating uterine contractions. Consult with a doctor before using senna during pregnancy. |
| Safety in breastfeeding | Limited data exists on the safety of senna use during breastfeeding. It is prudent to avoid or use senna only when clinically indicated after consultation with a physician. Check with a doctor before using. |
| side effects | | 1 | abdominal cramps | | 2 | diarrhea | | 3 | gas | | 4 | nausea | | 5 | vomiting | | 6 | stomach pain | | 7 | dehydration (if used excessively or for prolonged periods) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to senna or any of its components. | | 2 | Severe dehydration or electrolyte imbalance. | | 3 | Intestinal obstruction or other conditions that obstruct the digestive tract. | | 4 | Acute abdominal pain or symptoms suggestive of a serious medical condition. |
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| interactions | | 1 | Other laxatives may potentiate senna's effects. Do not use more than one laxative product without consulting a physician | | 2 | May interact with certain medications or supplements - consult with a physician |
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| warnings and precautions | | 1 | Do not use for more than a few days without consulting a doctor. Prolonged use may lead to dependence and cause electrolyte imbalances. Check with your doctor | | 2 | May interfere with the absorption of certain medications | | 3 | Patients with underlying digestive issues should exercise caution and consult with a physician |
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| additional informations | This information is for general knowledge only. It is not a substitute for professional medical advice. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition or treatment. This information should not be used to diagnose or treat any medical problem or disease. Consult a physician before self-medicating. |
