| name | Polyethylene Glycol (PEG) Electrolyte Solution |
| classification | Laxative, osmotic |
| pharmacokinetics | PEG is not absorbed systemically. It acts locally in the colon by drawing water into the stool, increasing stool volume and softening it. The exact duration of action varies but is generally hours to days. Elimination is via the feces. |
| suggested dosage | Dosage varies based on indication and severity of constipation. Consult with a healthcare professional. Typical initial dosage ranges from 17.5 grams to 30 grams (30 mL to 60 mL solution) as a single dose or divided doses, depending on the specific product. Some oral electrolyte PEG solutions may have specific dosing instructions in the product information. |
| indications | Short-term treatment of constipation, bowel cleansing preparation for colonoscopy, or other procedures requiring empty bowel. |
| safety in pregnancy | Limited data available. Consult with a healthcare professional. Generally considered safe if used as directed and for short duration. |
| safety in breastfeeding | Limited data available. Consult with a healthcare professional. Generally considered safe if used as directed and for short duration. |
| side effects | | 1 | Abdominal cramps | | 2 | Nausea | | 3 | Vomiting | | 4 | Bloating | | 5 | Diarrhea (ranging from mild to severe, depending on dose) | | 6 | Dehydration if used for prolonged period or excessive dosage | | 7 | Electrolyte imbalance if used repeatedly or for extended periods (especially in patients with underlying kidney or liver disease) |
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| alternatives | |
| contraindications | | 1 | Severe dehydration | | 2 | Known hypersensitivity or allergy to PEG or other components of the solution | | 3 | Intestinal obstruction or perforation | | 4 | Severe electrolyte disturbances |
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| interactions | | 1 | May alter absorption of other medications taken orally at the same time | | 2 | Concurrent use with other laxatives may lead to increased side effects, especially diarrhea. |
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| warnings and precautions | | 1 | Monitor for signs of dehydration (e.g., excessive thirst, decreased urine output, dizziness). | | 2 | Appropriate hydration is crucial if consuming PEG for a prolonged period or as high dosage | | 3 | Use cautiously in patients with electrolyte disorders or renal impairment. Consult with a healthcare professional | | 4 | Monitor fluid and electrolyte levels in patients with pre-existing kidney or liver conditions, if PEG is used repeatedly | | 5 | Do not use longer than recommended or exceed the dosage. If constipation persists, consult a medical professional. | | 6 | If side effects such as severe abdominal pain, vomiting, fever or blood in stool occur, stop using and consult your doctor. |
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| additional informations | | 1 | Comes in various formulations and concentrations. It is important to use the correct type and amount for the intended use. | | 2 | Always read the patient information leaflet provided with the product for specific dosing instructions | | 3 | Patient's age, weight and overall health can affect the dosage and response to the treatment. |
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| patient profile | |
