| name | Salicylic Acid |
| classification | Keratolytic, Anti-inflammatory, Analgesic (topical) |
| pharmacokinetics | Salicylic acid is readily absorbed through the skin. Its primary site of action is the stratum corneum, where it inhibits keratinization and promotes desquamation. The extent of systemic absorption varies depending on the concentration, site of application, and duration of contact. Topical application is generally well tolerated, with minimal systemic absorption. |
| suggested dosage | Dosage depends heavily on the formulation and condition being treated. Consult a healthcare professional for appropriate guidance. Typical topical applications involve applying a thin layer to the affected area as directed by the product label or a physician. Do not exceed recommended usage. |
| indications | | 1 | Acne vulgaris (topical) | | 2 | Calluses and corns (topical) | | 3 | Psoriasis (topical) | | 4 | Warts (topical) | | 5 | Actinic keratosis (topical) |
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| safety in pregnancy | Limited human data exists. Salicylic acid may be used topically, but avoid systemic use during pregnancy. Consult a doctor before use if pregnant or trying to conceive. |
| safety in breastfeeding | Limited data, but possible excretion in breast milk. Topical use should be used with caution and should be avoided if possible. Consult a doctor before use if breastfeeding. |
| side effects | | 1 | Skin irritation (common, especially with higher concentrations) | | 2 | Skin redness (erythema) | | 3 | Skin dryness | | 4 | Stinging or burning sensation | | 5 | Exfoliation (peeling) | | 6 | Allergic reactions (rare) | | 7 | Rarely, systemic effects may occur if absorbed in high doses. Such effects may include nausea, vomiting, diarrhea, and fever. |
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| alternatives | |
| contraindications | | 1 | Known allergy to salicylic acid or salicylates | | 2 | Open wounds or broken skin in the application area (may worsen or cause burns). | | 3 | Use caution with impaired skin barrier or eczema | | 4 | Severe hepatic or renal impairment (may require reduced or avoided dose) |
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| interactions | May interact with other topical medications. Do not use with other topical keratolytics unless specifically advised by a physician. Consider possible interactions if taking other systemic medications. Consult a doctor. |
| warnings and precautions | | 1 | Avoid contact with eyes. If contact occurs, flush with copious amounts of water. | | 2 | Do not apply to large areas of skin without medical advice. | | 3 | Use as directed. Do not increase dosage or frequency without consulting a doctor. | | 4 | Use caution when using in children or on delicate skin. |
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| additional informations | | 1 | Available in various concentrations and formulations (e.g., creams, lotions, ointments, pads). | | 2 | For topical use only. Do not ingest. |
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| patient specific considerations | | age 25 weight 70kg | General recommendations for salicylic acid topical application apply to a healthy male patient of 25 years and 70 kg. However, individual responses may vary. Consult a doctor for personalized advice, especially if underlying skin conditions exist. |
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