| name | Pyrantel Pamoate |
| classification | Anthelmintic |
| pharmacokinetics | Pyrantel pamoate is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are typically reached within 1-2 hours. It primarily targets the neuromuscular junction of parasitic worms, leading to paralysis and expulsion. The drug is eliminated primarily through the feces, with some metabolism occurring in the liver. |
| suggested dosage | | adult | Based on the patient's weight, the typical dosage for pyrantel pamoate would be 10-11 mg/kg (or 500mg to 600mg for a 70kg adult) of the medication, given once. A second dose may be necessary based on the severity and type of infection. | | child weight based | Consult a medical professional for dosing. Dosing of children should be based on the specific weight of the child, and is frequently expressed in milligrams per kilogram of body weight. |
|
| indications | Pyrantel pamoate is primarily indicated for the treatment of infections caused by roundworms (ascaris), hookworms (ancylostoma), pinworms (enterobius), and whipworms (trichuris). It is also used for threadworm infections. |
| safety in pregnancy | Pyrantel pamoate is generally considered safe for use during pregnancy. However, it is crucial to discuss the use of this drug with a physician, especially during the first trimester. Limited clinical data regarding its use in various stages of pregnancy does not conclusively prove or disapprove safety. Consult your doctor for specific advice. |
| safety in breastfeeding | Pyrantel pamoate is generally considered safe for use during breastfeeding. However, it is crucial to discuss the use of this drug with a physician. Small amounts of the drug may pass into breast milk; this should be carefully weighed against potential benefits of treatment versus any potential risks to the baby. |
| side effects | | 1 | Headache | | 2 | Nausea | | 3 | Vomiting | | 4 | Diarrhea | | 5 | Abdominal pain | | 6 | Loss of appetite | | 7 | Fatigue | | 8 | Dizziness | | 9 | Skin rash | | 10 | Allergic reactions (rare) |
|
| alternatives | |
| contraindications | | 1 | Known hypersensitivity to pyrantel pamoate or other components of the medication | | 2 | Severe liver or kidney disease (use with caution) |
|
| interactions | Limited significant drug interactions are known, however, it's important to inform your doctor of any other medications you're taking. |
| warnings and precautions | | 1 | Pyrantel pamoate is generally safe, but some caution is necessary in individuals with liver or kidney impairment. Follow your doctor's instructions meticulously. | | 2 | Do not use this drug for other than indicated uses, as this may lead to problems. |
|
| additional informations | Pyrantel pamoate is usually taken orally. |
| patient specific details | |
