| name | Albendazole |
| Classification | Anthelmintic |
| Pharmacokinetics | Albendazole is absorbed poorly from the gastrointestinal tract. Peak plasma concentrations are achieved within 1-2 hours after oral administration. The drug is extensively metabolized in the liver, primarily by oxidation, and its metabolites are also active. The primary route of excretion is through the urine, and a small fraction is excreted in the feces. The half-life of albendazole is variable, ranging from 8 to 20 hours, and it is dependent on the specific formulation and patient factors. |
| suggested dosage | | general | Dosage varies depending on the indication and the specific formulation (tablets, suspensions). Consult a physician for the appropriate dosage based on the patient's condition and weight. The information provided here is not a substitute for medical advice. | | example dosage | For example, in cases of ascariasis, albendazole 400 mg as a single dose is often sufficient. For other indications, different schedules and durations may be required. |
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| indications | | 1 | Roundworm infections (ascariasis) | | 2 | Hookworm infections | | 3 | Whipworm infections | | 4 | Pinworm infections (enterobiasis) | | 5 | Hydatid cyst infection | | 6 | Strongyloidiasis |
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| Safety in pregnancy | Albendazole is generally considered safe for use in pregnancy, particularly during the later stages, with proper medical supervision. However, there are limited data on use during the first trimester. Consult a physician for guidance if pregnant or planning a pregnancy. |
| Safety in breastfeeding | Albendazole may pass into breast milk. Although not reported to cause significant adverse effects in infants, it is best to consult a physician regarding the potential risks and benefits of use during breastfeeding. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal pain | | 5 | Headache | | 6 | Fatigue | | 7 | Loss of appetite | | 8 | Skin rash | | 9 | Elevated liver enzymes (rare) | | 10 | Allergic reactions (rare) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to albendazole or any of its components | | 2 | Severe liver disease | | 3 | Severe kidney disease |
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| interactions | | 1 | Certain medications (e.g., some anti-HIV medications, other anthelmintics) may affect the metabolism of albendazole and require dose adjustments. | | 2 | Consult with a physician about any medications the patient is currently taking. |
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| warnings and precautions | | 1 | Monitor for signs of liver dysfunction during treatment. | | 2 | May cause dizziness or lightheadedness, especially in combination with other medications. Patient should be advised accordingly. | | 3 | Caution is needed in patients with compromised renal function. |
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| additional information | Proper diagnosis and medical supervision are crucial for appropriate treatment with albendazole. Dosage and duration of treatment depend on the specific infection and patient response. This information is for educational purposes only and does not constitute medical advice. |
| patient specific details | | age | 25 years | | weight | 70 kg | | note | This information is general. A healthcare professional should tailor the dosage and treatment plan to the individual patient needs. |
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