| name | Lansoprazole |
| classification | Proton Pump Inhibitors (PPIs) |
| pharmacokinetics | Lansoprazole is rapidly absorbed after oral administration. Peak plasma concentrations are typically reached within 1-2 hours. It is extensively metabolized in the liver, primarily via CYP2C19. The active metabolite is further metabolized, and the primary route of elimination is through the liver, primarily as inactive metabolites in the bile and urine. |
| suggested dosage | | general | The typical dosage for adults is 15-30 mg once daily, but may vary depending on the specific condition being treated. | | specific conditions | | 1 | | condition | Gastroesophageal Reflux Disease (GERD) | | dosage | 15 mg once daily, or 30 mg once daily, depending on severity |
| | 2 | | condition | Peptic Ulcer Disease | | dosage | 15-30 mg once daily for 4-8 weeks |
| | 3 | | condition | Zollinger-Ellison syndrome | | dosage | 60 mg once daily, or higher doses may be necessary |
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| | patient specific notes | Dosage should be individualized based on the patient's response and the severity of the condition. Consult with a healthcare professional for appropriate dosage for a 25-year-old male weighing 70kg. |
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| indications | Lansoprazole is used to treat conditions where excess stomach acid is a factor, such as gastroesophageal reflux disease (GERD), peptic ulcers, Zollinger-Ellison syndrome, and other conditions. |
| safety in pregnancy | Lansoprazole use in pregnancy should be avoided whenever possible. If absolutely necessary, it should be used only under the strict supervision of an obstetrician. Limited data exists on the risk of birth defects, but theoretically, it could cause some fetal harm, particularly in the first trimester. Consult a healthcare provider. |
| safety in breastfeeding | Lansoprazole is excreted in breast milk in small amounts. The potential risk to the infant is considered low, but breastfeeding mothers should discuss its use with their healthcare provider. |
| side effects | | 1 | Headache | | 2 | Diarrhea | | 3 | Constipation | | 4 | Nausea | | 5 | Abdominal pain | | 6 | Vomiting | | 7 | Dizziness | | 8 | Skin rash | | 9 | Infections (especially pneumonia, community-acquired) | | 10 | Vitamin B12 deficiency (long-term use) | | 11 | Rare cases of serious liver problems |
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| alternatives | |
| contraindications | Known hypersensitivity to lansoprazole or other similar drugs. |
| interactions | | 1 | Drugs metabolized by CYP2C19 (e.g., some antidepressants, clopidogrel) | | 2 | Drugs that can decrease gastric acidity (e.g., H2 receptor antagonists) | | 3 | Drugs that can increase gastric acidity (e.g., some NSAIDs) |
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| warnings and precautions | Long-term use may be associated with a slight increased risk of bone fractures and vitamin B12 deficiency, although the mechanisms aren't fully understood. Caution should be exercised in patients with pre-existing liver disease or a history of such conditions. |
| additional informations | Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements. Always follow the prescribed dosage and duration of treatment as advised by the healthcare professional. |
| patient specific considerations age weight | The provided dosage information is a general guideline. A healthcare provider should determine the appropriate dosage for a 25-year-old male weighing 70kg based on the specific medical condition being treated. |
| important note | This information is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional before starting any new medication. |
