name | Fluticasone Propionate |
classification | Corticosteroid, inhaled |
pharmacokinetics | Fluticasone propionate is a potent corticosteroid primarily absorbed locally in the lungs. A small amount is systemically absorbed, with plasma concentrations varying based on dosage and patient lung function. Absorption is rapid, with peak concentrations occurring within minutes to hours of inhalation. Metabolism primarily occurs in the liver, and excretion occurs primarily via the kidneys. |
dosage | note | Dosage must be determined by a qualified healthcare professional. Do not self-medicate. | specific dosing | Dosage depends on the specific condition being treated. A physician should determine the precise dosage based on patient needs and response. Generic guidelines are not applicable due to the wide range of indications. |
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indications | Fluticasone propionate is primarily used for asthma and other respiratory conditions, such as chronic obstructive pulmonary disease (COPD). It may also be used in some cases of allergic rhinitis. |
safety in pregnancy | note | Use with caution. Potential fetal risks require discussion with a physician. Use the lowest effective dose for the shortest duration possible. |
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safety in breastfeeding | note | Limited data on excretion in breast milk. Use is not recommended unless benefits outweigh potential risks to the infant. Monitor infant for adverse effects. Consider alternative treatments where possible. |
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side effects | 1 | type | common | effects | 1 | Throat irritation | 2 | Cough | 3 | Hoarseness | 4 | Oral candidiasis (thrush) | 5 | Headache | 6 | Nasal congestion |
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| 2 | type | less_common | effects | 1 | Facial flushing | 2 | Systemic effects (e.g., hyperglycemia, adrenal suppression) |
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| 3 | type | rare | effects | 1 | Rash | 2 | Skin dryness | 3 | Other serious side effects (always consult your physician) |
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alternatives | |
contraindications | Known hypersensitivity to fluticasone propionate or other corticosteroids. Severe systemic infections, uncontrolled diabetes, and certain other underlying health issues require careful evaluation and dosage adjustments by a physician. |
interactions | May interact with other medications, including other corticosteroids. Full disclosure of all medications is essential. Consult your physician. |
warnings and precautions | 1 | Not for oral use. | 2 | Use proper inhaler technique for maximum effectiveness and minimized side effects. | 3 | Do not stop use abruptly without consulting your physician. | 4 | Monitor for signs of adrenal insufficiency (especially with long-term use). | 5 | Patients with weakened immune systems may be at higher risk of infections. |
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administration | Typically administered via inhalation. Dosing varies based on disease severity. Initial doses are often lower and gradually adjusted as needed by a healthcare provider. |
additional information | Proper inhaler technique is crucial. Always consult with a physician or pharmacist for personalized guidance. This information is for general knowledge only; consult a healthcare professional for specific medical advice. |