| name | Aspirin |
| Classification | Nonsteroidal anti-inflammatory drug (NSAID), Antiplatelet agent |
| Pharmacokinetics | Aspirin is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are typically reached within 30 minutes to 2 hours after oral administration. It is widely distributed throughout the body, and is metabolized primarily in the liver. The half-life of aspirin varies depending on the dose and route of administration, typically ranging from 15 to 30 minutes for low doses. A significant portion of aspirin is excreted unchanged in the urine. |
| suggested dosage | | adult male 25y 70kg | | pain relief | 325-650 mg every 4-6 hours as needed, maximum daily dose 4 grams. | | prevention of heart attack or stroke | 81 mg daily | | other indications | Dosage will depend on the specific indication. Consult a doctor or pharmacist for appropriate dosage. |
| | important note | Always follow the prescribed dosage by a healthcare professional. Self-medication with aspirin can be harmful. |
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| indications | | 1 | Pain relief (headache, muscle aches, toothache) | | 2 | Fever reduction | | 3 | Reduction of inflammation (e.g., arthritis) | | 4 | Prevention of heart attack and stroke (low dose) | | 5 | Treatment of pericarditis and other inflammatory conditions. |
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| safety in pregnancy | Aspirin use during pregnancy should be carefully considered and only under the direct supervision of a physician. Aspirin may cause harm to the fetus in some stages of pregnancy. Avoid use in the third trimester unless critically necessary. |
| safety in breastfeeding | Aspirin use during breastfeeding is not recommended, due to the potential for the drug to enter the breast milk. Alternatives should be considered. |
| side effects | | 1 | Gastrointestinal upset (nausea, heartburn, stomach pain) | | 2 | Bleeding (from the stomach or other sites) | | 3 | Headache | | 4 | Dizziness | | 5 | Tinnitus | | 6 | Allergic reactions (rash, hives, anaphylaxis) | | 7 | Kidney problems in high doses or prolonged use | | 8 | Reye's syndrome (rare, but serious) particularly in children and adolescents with viral infections. |
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| alternatives | |
| contraindications | | 1 | Active peptic ulcer | | 2 | Bleeding disorders | | 3 | History of allergic reactions to aspirin or other NSAIDs | | 4 | Severe kidney disease | | 5 | Certain heart conditions (e.g., severe heart failure) |
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| interactions | | 1 | Other NSAIDs | | 2 | Anticoagulants (e.g., warfarin) | | 3 | Corticosteroids | | 4 | Diuretics | | 5 | Certain medications for blood pressure or blood thinners | | 6 | Lithium | | 7 | Methotrexate |
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| warnings and precautions | | 1 | Do not use aspirin if you have a history of allergic reaction or asthma related to aspirin. | | 2 | Use caution in patients with a history of gastrointestinal problems. | | 3 | Be aware of potential bleeding risks, especially if combined with other medications. | | 4 | Monitor kidney function if taking high doses or for extended periods. | | 5 | Inform your doctor about all medications and supplements you are taking. | | 6 | Do not use aspirin if you have a bleeding disorder or are considering surgery. | | 7 | Do not crush or chew coated aspirin unless directed by your physician. |
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| additional informations | Aspirin can be taken in different forms, including regular tablets, enteric-coated tablets, and chewable tablets. Always follow the instructions on the product label and consult a healthcare professional for proper use and to prevent potential complications. |
| important notes | This information is for educational purposes only and does not constitute medical advice. Always consult a doctor or pharmacist before starting any new medication. |
