| name | Acetaminophen (Paracetamol) |
| classification | Non-opioid analgesic and antipyretic |
| pharmacokinetics | | absorption | Rapidly absorbed from the gastrointestinal tract after oral administration. | | distribution | Distributed throughout the body, including the central nervous system and kidneys. | | metabolism | Primarily metabolized in the liver. | | excretion | Excreted mainly in the urine as glucuronide and sulfate conjugates. |
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| suggested dosage | | adult | Standard dose is 325-1000 mg every 4-6 hours as needed, not to exceed 4 grams per 24 hours. Specific dosage may vary based on patient condition and response. | | specific considerations | Consult a physician or pharmacist for precise dosage for your particular situation. |
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| indications | | 1 | Treatment of mild to moderate pain, such as headaches, muscle aches, and menstrual cramps. | | 2 | Reduction of fever. | | 3 | Treatment of symptoms associated with the common cold or flu. |
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| safety in pregnancy | Acetaminophen is generally considered safe for use in pregnancy during the first trimester, though potential risks to the fetus are not fully understood, especially with prolonged or high dosages. Discuss use with your healthcare provider. |
| safety in breastfeeding | Acetaminophen is considered safe for use in breastfeeding mothers when used at recommended dosages. |
| side effects | | 1 | Generally well-tolerated, but some individuals may experience nausea, vomiting, or constipation. | | 2 | Rarely, liver damage may occur, especially with overuse or combined use with other hepatotoxic medications. |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to acetaminophen. | | 2 | Severe liver disease. |
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| interactions | | 1 | Alcohol, other medications affecting the liver, or taking excessive doses of other medications. | | 2 | Use with caution if taking other pain medications. |
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| warnings and precautions | | 1 | Do not exceed recommended dosage. | | 2 | Use with caution in patients with impaired liver function. | | 3 | Monitor for signs of liver damage in individuals who consume excessive amounts of alcohol or take other medications that might affect the liver. | | 4 | Do not use if you have a known allergy to this medication. |
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| additional informations | | patient specific notes | A 25-year-old male weighing 70kg is considered a healthy adult. Always follow the instructions of your physician or pharmacist. | | important considerations | If symptoms persist or worsen, consult a healthcare professional immediately. |
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