| name | Mebendazole |
| classification | Antihelminthic (benzimidazole class) |
| pharmacokinetics | Mebendazole is rapidly absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours. It distributes throughout the body, including the gastrointestinal tract, where it accumulates in parasitic worms. Metabolism occurs primarily in the liver, and it is excreted primarily in the urine and feces. |
| dosage | | adult | | weight | 70 kg | | dosage | 500 mg twice daily for 3 days | | notes | Adjustments may be necessary based on individual patient factors and infection type. |
| | pediatric | Dosage in children varies by weight and age; consult a physician. | | instructions | Take with food to minimize gastrointestinal upset. Follow the prescribed course of treatment, even if symptoms improve. |
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| indications | | 1 | | infection | Roundworm (Ascaris lumbricoides) | | efficacy | Effective |
| | 2 | | infection | Pinworm (Enterobius vermicularis) | | efficacy | Effective |
| | 3 | | infection | Hookworm (Ancylostoma duodenale and Necator americanus) | | efficacy | Effective |
| | 4 | | infection | Whipworm (Trichuris trichiura) | | efficacy | Effective |
| | 5 | | infection | Other intestinal nematode infections | | efficacy | May be effective |
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| safety pregnancy | | caution | Limited data; use only if potential benefit outweighs risk. Consult a physician immediately. Do not use in the first trimester. | | additional notes | Consult with a healthcare professional if you are pregnant or planning a pregnancy. |
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| safety breastfeeding | | caution | Limited data; use with caution during breastfeeding. Consult a physician. | | additional notes | Potential for excretion into breast milk; consult with a healthcare professional |
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| side effects | | 1 | | symptom | Nausea | | severity | Mild to Moderate |
| | 2 | | symptom | Vomiting | | severity | Mild to Moderate |
| | 3 | | symptom | Abdominal pain | | severity | Mild |
| | 4 | | symptom | Diarrhea | | severity | Mild |
| | 5 | | symptom | Headache | | severity | Mild |
| | 6 | | symptom | Loss of appetite | | severity | Mild |
| | 7 | | symptom | Other gastrointestinal disturbances | | severity | May occur |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to mebendazole or other benzimidazoles | | 2 | Severe liver impairment | | 3 | Active or suspected pregnancy in first trimester |
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| interactions | | 1 | Possible interactions with some medications. Consult a physician or pharmacist. | | 2 | Example interaction: May decrease the effectiveness of certain anticonvulsants. (Consult physician for detailed list) | | 3 | Example interaction: May affect the absorption of certain drugs. Consult your physician about potential interactions with your current medications |
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| warnings and precautions | | 1 | Monitor for and report any unusual side effects. | | 2 | May cause some mild gastrointestinal side effects. | | 3 | Take with food. | | 4 | Avoid driving or operating machinery if dizziness or lightheadedness occurs. | | 5 | Inform your physician if you are taking other medications. | | 6 | Not recommended for long-term use unless indicated by a physician. |
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| additional information | | 1 | Adhere to the prescribed dosage and duration of treatment. | | 2 | Complete the entire course of treatment, even if symptoms disappear. | | 3 | Consult a physician for any possible complications. |
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| patient details | |
