1 | name | Acetaminophen | Classification | Non-opioid analgesic and antipyretic | Pharmacokinetics | Rapidly absorbed from the gastrointestinal tract, primarily metabolized in the liver. Elimination half-life varies depending on dose and individual factors. Plasma protein binding is low. | suggested dosage | Adults: 325-1000 mg every 4-6 hours as needed, not to exceed 4 grams in 24 hours. Consult a healthcare professional for specific dosage. | indications | Relief of mild to moderate pain, such as headaches, muscle aches, and osteoarthritis pain. Reduction of fever. | Safety in pregnancy | Generally considered safe in pregnancy during the recommended dose range. However, it's essential to discuss usage with a healthcare provider, especially during the first trimester. | Safety in breastfeeding | Generally considered safe in breastfeeding mothers at recommended dosages. However, consult with a healthcare professional to ensure safety for both the mother and infant. | side effects | Rarely, but potentially, liver damage (especially with high doses or prolonged use), skin rash. Rarely serious allergic reactions. | alternatives | | contraindications | Severe liver disease, known hypersensitivity to acetaminophen. Use cautiously in individuals with a history of alcohol abuse or significant alcohol consumption, as acetaminophen can cause liver damage. | interactions | Alcohol, some medications (e.g., certain anti-seizure medications, some antibiotics), should be discussed with a physician regarding potential interactions. | warnings and precautions | Follow recommended dosages carefully. Avoid exceeding the maximum daily dose. Monitor for any unusual signs of side effects. | additional information | Available over-the-counter in various strengths and formulations. Consult a physician for guidance. | patient specific considerations | Age, weight, and health status (e.g., kidney or liver disease) can influence dosage and safety. A healthcare professional can provide personalized recommendations. | patient data | |
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2 | name | Ibuprofen | Classification | Non-steroidal anti-inflammatory drug (NSAID) | Pharmacokinetics | Rapidly absorbed from the gastrointestinal tract. Metabolized in the liver. Elimination half-life varies. | suggested dosage | Adults: 200-400 mg every 4-6 hours as needed, not to exceed 1200 mg in 24 hours. Consult a healthcare professional for specific dosage. | indications | Relief of mild to moderate pain, such as headaches, muscle aches, and osteoarthritis pain. Reduction of fever. Treatment of some inflammatory conditions. | Safety in pregnancy | Generally considered relatively safe during pregnancy in recommended dosages. However, it's critical to discuss use with a healthcare provider, especially during the later stages of pregnancy. Avoid use close to delivery. | Safety in breastfeeding | Generally considered safe in breastfeeding mothers at recommended dosages. However, consult with a healthcare professional to ensure safety for both the mother and infant. | side effects | Gastrointestinal upset (e.g., nausea, heartburn, stomach pain), headache, dizziness, allergic reactions, and in rare cases, kidney problems. | alternatives | | contraindications | Known hypersensitivity to ibuprofen. Certain pre-existing conditions, including those involving the heart, blood pressure or kidneys, may necessitate adjustments in usage. Consult a doctor. | interactions | Certain medications (e.g., blood thinners, diuretics). Consult with a doctor about any medications taken to avoid interactions. | warnings and precautions | Avoid use in individuals with a history of stomach ulcers, gastrointestinal bleeding, or heart disease. Follow recommended dosages carefully. Monitor for any unusual signs of side effects. | additional information | Available over-the-counter in various strengths and formulations. | patient data | |
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3 | name | Naproxen | Classification | Non-steroidal anti-inflammatory drug (NSAID) | Pharmacokinetics | Rapidly absorbed from the gastrointestinal tract. Metabolized in the liver. Elimination half-life varies. | suggested dosage | Adults: 250-500 mg every 6-8 hours as needed, not to exceed 1250 mg/24hr. Consult a healthcare professional for specific dosage. | indications | Relief of mild to moderate pain, such as headaches, muscle aches, osteoarthritis pain, and menstrual cramps. | Safety in pregnancy | Generally considered relatively safe during pregnancy in recommended dosages. However, use should be carefully considered during all trimesters, and the risks and benefits must be discussed with a healthcare provider. Avoid use near delivery | Safety in breastfeeding | Generally considered safe in breastfeeding mothers at recommended dosages. However, consult with a healthcare professional to ensure safety for both the mother and infant. | side effects | Gastrointestinal upset (e.g., nausea, heartburn, stomach pain), headache, dizziness, allergic reactions, and rare cases of kidney problems. | alternatives | | contraindications | Known hypersensitivity to naproxen or other NSAIDs. Certain pre-existing conditions involving the heart, blood pressure, or kidneys may require adjustments in usage. Consult a doctor. | interactions | Certain medications (e.g., blood thinners, diuretics). Consult with a doctor about any medications taken to avoid interactions. | warnings and precautions | Avoid use in individuals with a history of stomach ulcers, gastrointestinal bleeding, or heart disease. Follow recommended dosages carefully. Monitor for any unusual signs of side effects. | additional information | Available over-the-counter and by prescription in various strengths and formulations. | patient data | |
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