| name | Tetracycline |
| Classification | Tetracycline Antibiotic |
| Pharmacokinetics | Tetracycline is absorbed from the gastrointestinal tract. Absorption is influenced by food, antacids, and other medications. Peak plasma concentrations are typically reached within 1-3 hours. The drug is widely distributed throughout the body, including tissues and fluids. Tetracycline is primarily excreted in the urine. The drug's half-life varies depending on the specific formulation and the patient's renal function. |
| suggested dosage | Dosage varies depending on the indication and the patient's condition. Consult a physician for specific dosage recommendations. For example, in adults, oral doses of 250-500 mg 4 times per day for infections of the skin, soft tissues, or respiratory tract are common. Important: Specific dosages should be determined by a healthcare professional and should not be self-administered. |
| indications | Tetracycline is used to treat a variety of bacterial infections, including infections of the skin, respiratory tract, urinary tract, and certain sexually transmitted infections (STIs). |
| Safety in pregnancy | Tetracycline is categorized as a Pregnancy Category D drug. It can cause discoloration of teeth and bone growth problems in the developing fetus. Use during pregnancy should only be considered if the potential benefits outweigh the potential risks. The healthcare provider should carefully weigh the risks and benefits with the patient. |
| Safety in breastfeeding | Tetracycline is excreted in breast milk. Because of the potential for adverse effects in infants, the use of tetracycline during breastfeeding is generally not recommended. |
| side effects | | 1 | Gastrointestinal upset (nausea, vomiting, diarrhea) | | 2 | Photosensitivity (increased skin sensitivity to sunlight) | | 3 | Discoloration of teeth (particularly in children) | | 4 | Superinfection (growth of resistant bacteria) | | 5 | Headache | | 6 | Vaginal yeast infection | | 7 | Allergic reactions (rash, hives, itching) |
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| contraindications | | 1 | Known hypersensitivity or allergy to tetracycline or other related antibiotics | | 2 | Severe liver or kidney disease | | 3 | Pregnancy (unless benefits outweigh the risks, as discussed above) | | 4 | Infants, especially premature infants (due to the risk of discoloration of teeth) | | 5 | Certain GI conditions which can be exacerbated by the drug | | 6 | Individuals taking medications that can interact with tetracycline |
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| interactions | | 1 | Certain antacids (aluminum, magnesium, calcium containing) | | 2 | Iron supplements | | 3 | Certain oral medications (including oral contraceptives) | | 4 | Digoxin | | 5 | Oral anticoagulants |
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| warnings and precautions | | 1 | Inform your physician of any allergies, current medications, or medical conditions. Especially important is a history of liver or kidney disease | | 2 | Take the medication with a full glass of water and on an empty stomach (at least 1 hour before or 2 hours after meals, to enhance absorption). | | 3 | Avoid exposure to direct sunlight or tanning beds when taking tetracycline due to the potential for photosensitivity. Use sunscreen when outdoors. | | 4 | Report any unusual symptoms such as a worsening of symptoms, a rash, or changes in blood tests. | | 5 | Tetracycline can affect the developing teeth and bones, especially in children and pregnant women. Always follow the recommendations and advice of the physician |
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| additional informations | | 1 | Tetracycline is available in various forms, including tablets, capsules, and liquid suspensions. | | 2 | Long-term use of tetracycline may cause resistance to the drug. Thus the physician will assess the need for treatment. | | 3 | The provided information is not a substitute for professional medical advice. Always consult a healthcare provider before starting or stopping any medication, especially when treating a medical condition. |
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