| name | Salicylic Acid Topical |
| classification | Keratolytic, Anti-inflammatory |
| pharmacokinetics | Salicylic acid is readily absorbed through the skin. Its effect is primarily local. The extent of systemic absorption varies based on the concentration, vehicle, and duration of application. Higher concentrations and prolonged application may lead to increased systemic exposure. Excretion occurs primarily through the kidneys. |
| suggested dosage | Dosage depends heavily on the indication. Consult a physician for the appropriate concentration, frequency, and duration of application. Typical applications include 0.5-2% concentrations several times daily. Very high concentrations (up to 30%) are available for specific treatments, but should only be used under the supervision of a dermatologist. |
| indications | | 1 | Acne vulgaris | | 2 | Calluses | | 3 | Corns | | 4 | Warts | | 5 | Psoriasis (in conjunction with other therapies) | | 6 | Other skin conditions requiring keratolytic action |
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| safety in pregnancy | Limited data exists regarding salicylic acid's use during pregnancy. Use should be avoided, especially in the first trimester, unless the potential benefits outweigh the potential risks. Consult a physician if you are pregnant or planning to become pregnant. |
| safety in breastfeeding | Salicylic acid may be present in breast milk. Consult a physician before use if breastfeeding. |
| side effects | | 1 | Skin irritation | | 2 | Redness | | 3 | Burning | | 4 | Stinging | | 5 | Dryness | | 6 | Skin peeling (desquamation) | | 7 | Allergic reactions (rash, itching) | | 8 | Rarely, systemic effects such as headache, nausea or vomiting |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to salicylic acid | | 2 | Open or broken skin in the application area | | 3 | Use on large or sensitive areas without medical guidance | | 4 | Severe skin conditions or disorders |
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| interactions | Possible interactions with other topical medications; Consult a physician or pharmacist if using other topical or oral medications. |
| warnings and precautions | | 1 | Avoid contact with eyes and mucous membranes | | 2 | Use in low concentrations and for short durations, initially, for sensitive skin | | 3 | Apply a thin layer to the affected area | | 4 | Apply sunscreen in areas treated with salicylic acid | | 5 | Do not exceed recommended dose or duration without consulting a doctor |
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| additional informations | Salicylic acid should only be applied topically and not ingested. It's crucial to follow all instructions provided by the physician or pharmacist, and to report any unusual reactions immediately. The efficacy and safety depend significantly on proper application, dosage, and patient characteristics. |
