| name | Progestin-only contraceptives (POPs) |
| classification | Hormonal Contraceptives |
| pharmacokinetics | | absorption | Progestins are primarily absorbed from the gastrointestinal tract after oral administration, with variable bioavailability depending on the specific progestin. | | distribution | Progestins are distributed throughout the body, with high concentrations found in the reproductive organs. | | metabolism | The liver is the primary site of progestin metabolism, involving enzymatic pathways to inactive metabolites. | | excretion | Metabolites are primarily excreted in urine and feces. |
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| dosage | Dosage varies by formulation (pill, injection, implant). Consult a healthcare professional for appropriate recommendations. |
| indications | | 1 | Pregnancy prevention | | 2 | Management of heavy menstrual bleeding | | 3 | Treatment of certain gynecological conditions (e.g., endometriosis, PCOS) |
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| safety in pregnancy | Contraindicated. Do not use during pregnancy. |
| safety in breastfeeding | Generally safe with appropriate use, but effectiveness may vary. Consult a healthcare professional. |
| side effects | | 1 | Headache | | 2 | Breast tenderness | | 3 | Spotting or irregular bleeding (especially initially) | | 4 | Mood changes | | 5 | Weight changes | | 6 | Nausea | | 7 | Abdominal pain | | 8 | Changes in libido | | 9 | Migraine | | 10 | Serious side effects are rare; seek immediate medical attention for severe symptoms |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to progestins | | 2 | History of blood clots | | 3 | Severe liver disease | | 4 | Undiagnosed abnormal uterine bleeding | | 5 | Certain cancers (e.g., breast, endometrial) | | 6 | Pregnancy |
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| interactions | | 1 | Certain medications (e.g., anticonvulsants, antibiotics) | | 2 | May decrease effectiveness of other medications |
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| warnings and precautions | | 1 | Regular check-ups, especially the first year | | 2 | Accurate menstrual cycle tracking | | 3 | Be aware of potential side effects and contact a healthcare professional if they persist or worsen | | 4 | Caution advised in individuals with cardiovascular risk factors |
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| additional information | | patient specific details | | 1 | Example: Age 25, Weight 70 kg. Specific details about pre-existing conditions are needed for tailored recommendations. |
| | important notes | This information is for general knowledge only and does not constitute medical advice. Always consult a qualified healthcare professional for personalized recommendations and any health concerns related to progestin-only contraceptives. |
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| patient recommendations | | 1 | Consult your doctor to discuss suitability based on your health status. | | 2 | Provide your complete medical history to your doctor. | | 3 | Strictly follow prescribed dosage instructions. |
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