| name | Depo-Provera (Depot medroxyprogesterone acetate) |
| classification | Hormonal Contraceptive, Injectable |
| formulation | Depot medroxyprogesterone acetate (DMPA) suspension for intramuscular or subcutaneous injection |
| pharmacokinetics | DMPA is injected intramuscularly or subcutaneously. Slow release into the bloodstream provides contraceptive effect for approximately 12 weeks. Absorption is rapid, reaching peak concentration in a few hours. Metabolism primarily occurs in the liver, with elimination through renal and metabolic pathways. Specific pharmacokinetic parameters (e.g., half-life, volume of distribution) may vary by formulation and patient characteristics. Consult prescribing physician for details. |
| dosage | 150 mg DMPA suspension, administered intramuscularly or subcutaneously every 12 weeks. Dosage and frequency may vary based on specific product formulation; consult with prescribing physician. |
| indications | Prevention of unintended pregnancy. |
| pregnancy category | X (contraindicated in pregnancy) |
| safety in pregnancy | Contraindicated. Discontinue immediately and consult a physician if pregnancy occurs while using this medication. Significant risk to the fetus. |
| safety in breastfeeding | May affect milk production. Consult healthcare provider for potential benefits and risks. |
| side effects | | 1 | | effect | Weight gain | | frequency | Possible |
| | 2 | | effect | Mood changes | | frequency | Possible |
| | 3 | | effect | Headache | | frequency | Possible |
| | 4 | | effect | Breast tenderness | | frequency | Possible |
| | 5 | | effect | Irregular bleeding (spotting or breakthrough bleeding) | | frequency | Possible |
| | 6 | | effect | Bone mineral density changes (potential for decreased density) | | frequency | Possible |
| | 7 | | effect | Rare serious infections (including allergic reactions) | | frequency | Rare |
| | 8 | | effect | Nausea | | frequency | Possible |
| | 9 | | effect | Abdominal pain | | frequency | Possible |
| | 10 | | effect | Hair loss | | frequency | Possible |
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| alternatives | |
| contraindications | | 1 | Known or suspected pregnancy | | 2 | History of blood clots (thrombosis) | | 3 | Severe liver disease | | 4 | Allergy to DMPA | | 5 | Breast or uterine cancer | | 6 | Undiagnosed vaginal bleeding | | 7 | Severe kidney disease |
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| interactions | | 1 | | interaction | Certain medications may alter the efficacy of DMPA. Consult with the prescribing physician about all medications the patient is taking. | | mechanism | May increase or decrease the metabolism of DMPA |
| | 2 | | interaction | DMPA can interfere with some laboratory tests. | | mechanism | Consult the laboratory for specific details. |
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| warnings and precautions | | 1 | | warning | Regular check-ups and monitoring are essential for assessing the effectiveness and safety of the medication. It's essential to assess the potential risks and benefits for each individual. | | monitoring | Regular physical exams, blood tests, and assessment of blood clotting risk. |
| | 2 | History of stroke or heart conditions may require careful consideration | | 3 | Patients with a history of osteoporosis should be carefully assessed. | | 4 | DMPA can take up to a year for the body to return to normal after discontinuation. |
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| additional informations | The effectiveness and side effects may vary between individuals. Consult a healthcare professional for personalized advice. |
| patient information | | age | 25 | | weight | 70 | | other health conditions | N/A | | medical history | N/A | | allergies | N/A |
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| disclaimer | This information is for general knowledge and educational purposes only, and does not constitute medical advice. Always seek the advice of a qualified healthcare professional for any questions about your particular circumstances. |
