| name | Progesterone-only pills (POPs) |
| classification | Hormonal Contraceptives |
| pharmacokinetics | Progesterone, the active ingredient in POPs, is primarily metabolized in the liver. Absorption is relatively rapid after oral administration. The drug's half-life varies depending on the specific POP formulation. The primary excretion route is through the liver via bile. The body's response can vary based on individual metabolism and other factors. |
| suggested dosage | The specific dosage and regimen will depend on the particular brand and formulation of POPs. It's crucial to follow the instructions provided in the patient information leaflet and as directed by a healthcare professional. Common regimens involve a daily dose of the hormone. Patients should be meticulous in taking their medication at a consistent time each day to maintain the effectiveness of the contraceptive. |
| indications | Primary indication is contraception, preventing pregnancy. It may have some additional uses in treating conditions associated with hormonal imbalances such as menorrhagia (heavy periods) or endometriosis, but these secondary uses should be discussed with a doctor. |
| safety in pregnancy | POPs are *not* indicated for use during pregnancy. If a woman becomes pregnant while using POPs, it's crucial to seek medical advice immediately. |
| safety in breastfeeding | Generally considered safe for breastfeeding women. Some studies show minimal impact on breast milk levels, and it's often a preferred method of contraception for women who are breastfeeding. Always consult with a healthcare professional to discuss suitability. |
| side effects | | 1 | Irregular bleeding (spotting or breakthrough bleeding), which often resolves after a few months of use | | 2 | Mood changes (mild) | | 3 | Headache | | 4 | Breast tenderness | | 5 | Nausea or vomiting | | 6 | Weight changes (minor) | | 7 | Abdominal pain | | 8 | Changes in libido (sex drive) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to progestins or any component of the drug. | | 2 | History of blood clots (thrombosis). | | 3 | Severe liver disease. | | 4 | Undiagnosed vaginal bleeding. | | 5 | Known or suspected pregnancy |
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| interactions | Some medications, such as certain antibiotics, may slightly alter the effectiveness of POPs. Consult with a pharmacist or doctor about any other medications you're taking to avoid potential drug interactions. |
| warnings and precautions | | 1 | Regular check-ups with a healthcare professional are advised, especially in the first few months. | | 2 | Missed doses can affect effectiveness. Consult with the doctor if there's a missed dose or more than a few days of irregular bleeding. | | 3 | The pill might not immediately prevent pregnancy, so other methods of contraception might be needed for initial days of use. | | 4 | If you experience any persistent or severe side effects, stop use and contact your healthcare professional immediately. |
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| additional informations | POPs are typically available as a monthly pill regime. |
| patient profile | |
