| name | Polyethylene Glycol (PEG) |
| classification | Laxative, osmotic |
| pharmacokinetics | Polyethylene glycol is orally administered and works by drawing water into the intestines, thereby softening the stool and promoting bowel movements. It is not absorbed systemically, meaning it's primarily eliminated in the feces. |
| suggested dosage | | adult male 25 70kg | Commonly 17-34 grams (1-2 packets of the standard commercially available oral solution), administered in a single dose or divided doses. Individualized dosing is essential; consult a healthcare professional. | | important note | Dosage should be adjusted based on individual response and should not be exceeded without medical supervision. |
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| indications | Used to treat constipation, particularly for preparation before medical procedures such as colonoscopy. Can also be used in certain conditions that impede the normal movement of stool through the bowels. |
| safety in pregnancy | Limited data exists on polyethylene glycol use during pregnancy. Although it's considered generally safe, consult with a healthcare provider for specific guidance. |
| safety in breastfeeding | Limited data suggests it is likely safe in breastfeeding mothers, but further research is needed. Consult with your doctor. |
| side effects | | 1 | abdominal cramps | | 2 | bloating | | 3 | diarrhea | | 4 | nausea | | 5 | vomiting | | 6 | headache |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to polyethylene glycol | | 2 | Severe dehydration or electrolyte imbalance | | 3 | Intestinal obstruction |
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| interactions | | 1 | Can potentially interact with other medications that affect bowel function. Consult your healthcare provider to avoid potential drug interactions | | 2 | May impact the absorption of certain medications if taken together. This is especially pertinent with medications taken orally. |
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| warnings and precautions | | 1 | Use with caution in patients with kidney problems as the excretion may be affected. | | 2 | Do not use PEG as a long-term treatment for chronic constipation without medical advice. Chronic constipation should be investigated and treated by a healthcare professional. | | 3 | Monitor for signs of dehydration during and after use, especially in individuals prone to it. | | 4 | May interact with certain medications; always inform your healthcare provider about all medications you are taking. |
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| additional informations | | 1 | Different formulations and administration methods exist. Always follow the instructions provided by the manufacturer. | | 2 | A gradual increase in dosage is advised to minimize initial side effects, such as diarrhoea. | | 3 | PEG can be an effective treatment for constipation, but it's crucial to consult a medical professional, especially if experiencing persistent or severe symptoms, or if other health issues are present. |
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| patient specific considerations | | age and weight | The provided age and weight are considered when suggesting a dosage. However, specific dosage needs can vary, so always consult a healthcare professional for personalized recommendations. | | pre-existing conditions | Important to discuss any pre-existing medical conditions with a healthcare provider before starting PEG treatment. |
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