| drug details | | 1 | | name | Hydrocortisone 1% | | Classification | Corticosteroid, Topical | | Pharmacokinetics | Hydrocortisone is readily absorbed through the skin. The extent of absorption varies depending on the concentration, duration of use, and the area of application. Metabolism primarily occurs in the liver, with minimal excretion in the urine. | | suggested dosage | Apply a thin film to the affected area 1-2 times daily, or as prescribed by a physician. | | indications | Treatment of mild to moderate inflammatory skin conditions such as eczema, contact dermatitis, and pruritus (itching). | | safety in pregnancy | Generally considered safe for use during pregnancy, but use only as directed by a physician. Avoid prolonged or high-dose use. | | safety in breastfeeding | Limited data available; it's best to consult a physician. | | side effects | | 1 | Skin irritation (e.g., redness, dryness, burning, itching) | | 2 | Thinning of the skin (atrophy) | | 3 | Striae (stretch marks) | | 4 | Acne | | 5 | Telangiectasia (visible blood vessels) | | 6 | Systemic effects (rare, with prolonged use or large areas) | | 7 | Cushing's syndrome |
| | alternatives | | | contraindications | Active skin infections, hypersensitivity to corticosteroids, use over large areas for prolonged periods without physician supervision. | | interactions | May interact with other topical medications, but typically no major interactions with oral medications. | | warnings and precautions | Avoid contact with eyes. Do not use in children without explicit medical advice. Monitor for signs of increased inflammation or infection. Discontinue use and contact physician if symptoms worsen or new symptoms develop. Do not use occlusive dressings unless prescribed. | | additional informations | Hydrocortisone 1% cream is typically a first-line treatment for many inflammatory skin conditions. Strength and formulation can be adjusted depending on the specific condition and location. It is important to follow the prescribed dosage instructions carefully and to avoid overuse, as this can lead to skin thinning and other side effects. | | patient specific considerations | Age and weight are not significant factors in the general usage of topical hydrocortisone. The treatment approach should be individualized based on the specific condition and its severity, as well as possible interactions with any other medications the patient may be taking. Consult a physician before using topical treatments, especially if there are concerns about allergies, the possibility of skin infections, or if the skin condition is not resolving. |
| | 2 | | name | Coal Tar | | Classification | Keratolytic | | Pharmacokinetics | Coal tar is a complex mixture of chemicals. Its absorption through the skin is slow but it can be absorbed. Metabolism and excretion are complex. | | suggested dosage | Apply to affected area as directed by physician. Often a daily application, but varying depending on severity and type of condition. | | indications | Treatment of seborrheic dermatitis, psoriasis, and certain types of eczema. | | safety in pregnancy | Limited data available. Use only as directed by a physician, avoiding prolonged exposure. | | safety in breastfeeding | Limited data available. Use only under direct medical supervision. | | side effects | | 1 | Skin irritation (e.g., redness, dryness, burning, itching) | | 2 | Black or brown staining of skin | | 3 | Contact dermatitis |
| | alternatives | | | contraindications | Sensitivity to coal tar or any of its components. Do not use near eyes or mucous membranes | | interactions | May interact with other topical medications. Check with physician. | | warnings and precautions | Avoid contact with eyes and mucous membranes. Discontinue use if irritation develops. Coal tar can stain clothing. Apply in a well-ventilated area. | | additional informations | Coal tar can be an effective treatment for certain skin conditions, but can cause significant irritation and staining. It is important to follow physician directions closely. |
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