name | Clotrimazole |
Classification | Topical Antifungal |
Pharmacokinetics | Clotrimazole is a broad-spectrum antifungal agent that primarily acts locally by disrupting fungal cell membranes. Systemic absorption is minimal with topical use, however, prolonged or extensive use may result in some systemic effects. Specific pharmacokinetic data is not included due to the complexity and variable nature of topical absorption. |
suggested dosage | Apply a thin layer to the affected area 1-2 times daily, or as directed by a physician. The duration of treatment depends on the severity and type of infection. |
indications | Treatment of superficial fungal infections such as tinea pedis (athlete's foot), tinea cruris (jock itch), tinea corporis (ringworm), and in some cases of oral candidiasis (thrush) when applied to affected areas other than the mouth; treatment should be directed by a physician. |
Safety in pregnancy | Limited data exist. Consult a healthcare professional for appropriate use during pregnancy. Potential risks are generally considered low when used topically. |
Safety in breastfeeding | Limited data exist. Consult a healthcare professional before use if breastfeeding. |
side effects | Local reactions such as irritation, redness, burning, itching, and stinging are possible. Systemic effects are rare but can include allergic reactions, although serious systemic reactions are extremely uncommon with topical use. |
alternatives | |
contraindications | Hypersensitivity to clotrimazole or any of its ingredients. |
interactions | Limited interactions with topical medications. Disclose all medications to a physician to avoid potential interactions. |
warnings and precautions | Avoid contact with eyes. If irritation or allergic reaction occurs, discontinue use and seek medical attention. Discontinue use if infection worsens or symptoms don't improve after a few weeks. |
additional information | Apply to dry skin. Do not use in open wounds or broken skin. |
patient specific considerations | Age and weight are not major factors in dosage adjustments for topical antifungals. Always follow a physician's instructions and do not self-treat. |