| name | Neomycin Topical |
| classification | Antibiotic (Aminoglycoside) |
| pharmacokinetics | Neomycin is primarily a topical antibiotic. Absorption into systemic circulation is generally low when used topically, but can occur, especially with extensive skin damage, compromised skin barrier, or prolonged use. In the presence of intact skin, absorption is minimal. Metabolism is minimal and excretion primarily occurs via the kidneys. The specific pharmacokinetic parameters in a patient of 25 years old and 70 kg weight are not usually reported in details because systemic effects are considered minimal with topical applications. |
| suggested dosage | Dosage is determined by the severity and location of the infection, and should be applied as directed by the prescribing physician. Often, the product instructions (from the label) give dosage guidelines, but always follow the directions given by your doctor. Do not exceed the recommended dosage. |
| indications | Topical neomycin is indicated for treating superficial skin infections, including those caused by susceptible bacteria. This includes conditions like impetigo, cellulitis and some types of acne, when topical antibiotics are appropriate. It is important to note that topical antibiotics are not generally effective against viral or fungal infections. |
| safety in pregnancy | Limited data exists regarding the safety of neomycin during pregnancy. Although systemic absorption is generally low, the potential risk warrants caution. The decision to use neomycin during pregnancy should be made in consultation with the prescribing healthcare provider, carefully considering the potential benefits versus the potential risks to the mother and developing fetus. |
| safety in breastfeeding | Limited data exists on the safety of neomycin use in breastfeeding mothers. Neomycin, when used topically, has a very low likelihood of entering the breast milk. However, it's crucial to consult with a healthcare professional to weigh potential risks to the infant against the potential benefits of the medication for the mother. |
| side effects | | 1 | Skin irritation (e.g., redness, itching, burning, rash) | | 2 | Allergic reactions (e.g., hives, swelling, difficulty breathing) | | 3 | Contact dermatitis | | 4 | Superinfection (growth of resistant bacteria or fungi in the area of treatment) | | 5 | Systemic effects (rare) including kidney problems if significant systemic absorption occurs |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to neomycin or other aminoglycosides | | 2 | Significant skin damage or compromised skin barrier where systemic absorption might be increased |
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| interactions | Neomycin can interact with other medications, especially if absorption becomes systemic. Consult your doctor before using any other medications concurrently. If you have other medical conditions or are taking other medications, inform your doctor before using this medication. |
| warnings and precautions | | 1 | Use only as directed. Avoid contact with eyes. | | 2 | If symptoms worsen or do not improve, discontinue use and contact a healthcare provider. | | 3 | Do not use on open wounds or where skin is severely broken. | | 4 | Do not use for more than the recommended duration without consulting a healthcare provider. |
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| additional informations | This information is for general knowledge only and does not constitute medical advice. Always consult with a qualified healthcare provider for any health concerns or before making any decisions related to your health or treatment. Dosage, frequency, and duration of treatment should be determined in consultation with a healthcare professional. |
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