| name | Mupirocin |
| classification | Topical antibacterial |
| pharmacokinetics | Mupirocin is a topical antibiotic that works by inhibiting bacterial protein synthesis. It is primarily absorbed locally, with minimal systemic absorption. Metabolism primarily occurs at the application site and in the liver. Excretion is primarily through the biliary system, followed by renal excretion. |
| suggested dosage | Dosage depends on the indication and severity of infection. Consult a healthcare professional for specific instructions. General guidelines for topical application include applying a thin film of ointment 2-3 times per day for 2-5 days. The dosage for various conditions may differ. |
| indications | Mupirocin is indicated for the treatment of superficial skin infections caused by susceptible Gram-positive bacteria, such as: impetigo, cellulitis, minor skin abrasions, and certain types of boils (furuncles). |
| safety in pregnancy | Limited data is available on the safety of mupirocin during pregnancy. While the risk is likely low, careful consideration by a healthcare professional is recommended, particularly during the first trimester. |
| safety in breastfeeding | Mupirocin is considered generally safe for use in breastfeeding mothers. However, minimal systemic absorption allows for low risk of transfer into breast milk and potential for infant exposure. Still, it's wise to discuss its use with the healthcare provider. |
| side effects | Common side effects include skin irritation, redness, itching, burning, or stinging at the application site. These are usually mild and transient. Serious adverse events are rare. Contact your doctor immediately if you experience persistent or severe reactions, or any other unusual symptoms. |
| alternatives | |
| contraindications | Mupirocin should not be used in patients with known hypersensitivity or allergy to mupirocin or any of its components. It is essential to discontinue treatment and consult a physician if allergic symptoms or skin reactions arise. |
| interactions | Limited significant drug interactions are expected with mupirocin given its topical application. However, concurrent use with other topical medications or systemic therapies should be discussed with the prescribing physician to prevent any potential interactions. |
| warnings and precautions | Avoid contact with eyes. Use with caution in patients with compromised skin integrity. Do not use on large open wounds. Ensure proper hand hygiene before and after application. Do not use longer than recommended without consulting a healthcare professional. |
| additional informations | Mupirocin is typically effective in treating minor skin infections, but severe or persistent infections require a doctor's evaluation and potentially a different treatment. If symptoms worsen or do not improve, consult a healthcare provider. Mupirocin is not effective against viral or fungal skin infections. |
| patient profile | |
