| drug name | Magnesium Hydroxide (Milk of Magnesia) |
| classification | Antacid, laxative |
| pharmacokinetics | Magnesium hydroxide is poorly absorbed from the gastrointestinal tract. It primarily works by neutralizing stomach acid and increasing fecal bulk, promoting bowel movements. The majority of the administered dose is excreted unchanged in the feces. The bioavailability is low. Excretion primarily occurs via the feces. |
| suggested dosage | | adult | | mild constipation | 8-15 mL (1-2 teaspoons) every 4-6 hours as needed, up to a maximum of 4 times a day. | | severe constipation | 15-30 mL (2-4 teaspoons) every 4-6 hours as needed, up to a maximum of 4 times a day. | | heartburn/acid indigestion | 15-30 mL (2-4 teaspoons) as needed, up to 4 times a day. |
| | notes | Dosage should be adjusted based on individual needs and response. It's crucial to follow the directions on the product label and consult a healthcare professional if unsure about the proper dosage. |
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| indications | | 1 | Constipation | | 2 | Heartburn | | 3 | Acid indigestion | | 4 | Treatment of mild hyperacidity |
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| safety in pregnancy | Magnesium hydroxide is generally considered safe for use during pregnancy, but it is always best to consult a doctor or other qualified healthcare provider before taking any medication during pregnancy or breastfeeding. Limited data on adverse fetal effects. |
| safety in breastfeeding | Generally considered safe for use during breastfeeding. However, small amounts may be excreted into breast milk. Monitor infant for any unusual symptoms. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal cramps | | 5 | Flatulence | | 6 | Constipation (with prolonged use) | | 7 | Mild headache | | 8 | Metallic taste |
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| contraindications | | 1 | Severe kidney disease (due to potential for magnesium buildup) | | 2 | Known hypersensitivity to magnesium hydroxide or any of the inactive ingredients | | 3 | High doses should be avoided during prolonged periods or concurrent use with other magnesium-containing medications | | 4 | If taking other medications, consult a healthcare provider |
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| interactions | | 1 | Other magnesium-containing medications (increased risk of magnesium toxicity) | | 2 | Certain antibiotics (may affect absorption of both) | | 3 | Digoxin (may decrease digoxin levels) | | 4 | Thyroid medications (may interfere with thyroid hormone absorption) | | 5 | Calcium-containing medications (may decrease absorption of both) |
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| warnings and precautions | | 1 | Do not exceed recommended dosage. If symptoms worsen or persist, consult a physician. | | 2 | May cause dehydration if used excessively. Drink plenty of fluids while taking this medication. | | 3 | Use cautiously in patients with kidney impairment. | | 4 | May interfere with absorption of other medications. Inform your doctor of all medications you are taking. | | 5 | Do not take this medication before or after other medications without consulting your doctor. |
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| alternatives | |
| additional information | | 1 | May cause a darkening of the stool. | | 2 | Store at room temperature, away from moisture and heat. | | 3 | Always check the expiration date before use. | | 4 | Overdose potential exists. Seek medical advice if symptoms of overdose are observed. |
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