| name | Fucidin |
| classification | Lincosamides, Topical Antibiotic |
| pharmacokinetics | Fucidin is a topical antibiotic and its pharmacokinetics are largely dependent on the route of administration and the specific formulation. Systemic absorption is minimal with topical use. When absorbed, it is distributed throughout the body, with concentrations varying in different tissues. The drug is primarily eliminated in the urine, although some metabolites may be eliminated in the feces. Detailed pharmacokinetic data for specific formulations is needed and is not readily available in general summary format. |
| suggested dosage | Dosage is dependent on the specific condition being treated and the route of administration. Fucidin is primarily used topically, such as creams or ointments for localized skin infections. Consult a physician for proper dosage. |
| indications | Topical fucidin is primarily indicated for superficial skin infections caused by susceptible Gram-positive bacteria such as Staphylococcus aureus and Streptococcus species. Examples include impetigo, cellulitis, and minor skin infections. It is NOT indicated for systemic infections, and systemic use is not recommended. |
| safety in pregnancy | Limited data is available regarding the safety of topical fucidin use during pregnancy. While generally considered safe, consult with a healthcare provider before use, particularly during the first trimester, given the potential risk of unknown effects on the developing fetus. |
| safety in breastfeeding | Limited clinical data on fucidin's effects in breastfeeding mothers is available, and no conclusive evidence of safety or harm during breastfeeding is established. Always consult a healthcare professional before using the drug when breastfeeding. |
| side effects | | 1 | Local skin reactions (e.g., irritation, redness, burning, itching, rash) | | 2 | Allergic reactions (e.g., hives, skin rash, swelling) | | 3 | Rare cases of systemic effects if significant skin penetration occurs |
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| alternatives | |
| contraindications | | 1 | Hypersensitivity to fucidin or other lincosamides. | | 2 | Severe skin conditions such as significant skin lesions that are not directly accessible and could lead to systemic absorption |
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| interactions | Limited information regarding specific drug interactions is available, but it is prudent to inform your physician about all medications and supplements you are taking when topical fucidin is prescribed. Avoid concurrent use of potentially irritating topical agents on the same site unless specifically directed by a physician. |
| warnings and precautions | | 1 | Apply only to the affected area. Do not apply to large or open wounds. | | 2 | Do not use for prolonged periods without consulting a healthcare provider. | | 3 | Stop use and consult a physician if symptoms worsen or new symptoms arise. | | 4 | Use caution to ensure no significant penetration occurs, avoid using on extensive skin areas | | 5 | Use appropriate barriers for the skin and assess for reactions. | | 6 | In case of systemic absorption, monitor for adverse reactions. | | 7 | Use only as prescribed by a medical professional. |
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| additional information | Specific formulations of topical fucidin, such as creams, ointments, or solutions, may differ in their recommended usages and potential side effects. Always consult your healthcare provider about the appropriate use for a given condition. |
