| drug details | | class | Fluoroquinolones | | specific drug | | | general information | | classification | Antibacterial agents | | indications | Fluoroquinolones are indicated for a wide range of bacterial infections, including respiratory, urinary tract, skin, and bone infections. They are often used for treating infections caused by organisms resistant to other antibiotics. | | pharmacokinetics | Fluoroquinolones are generally well-absorbed orally. Absorption can be affected by food and other medications. They are distributed throughout the body, with varying concentrations in different tissues. Excretion is primarily through the kidneys. The pharmacokinetic profile varies significantly between individual fluoroquinolones, with differences in half-life, renal clearance, and tissue penetration. | | safety in pregnancy | Fluoroquinolones should be used during pregnancy only if the potential benefit outweighs the potential risk to the developing fetus. Data on long-term effects are limited, and some studies have shown potential adverse effects on fetal development. Consult the prescribing information and a healthcare professional for specific guidance. | | safety in breastfeeding | Fluoroquinolones can be excreted into breast milk. The potential risks to the infant should be carefully weighed against the potential benefits to the mother. Consult with a healthcare professional before using fluoroquinolones while breastfeeding. | | side effects | Common side effects can include nausea, vomiting, diarrhea, headache, dizziness, and abdominal pain. Serious side effects, though less common, can include tendon rupture (particularly in the Achilles tendon), peripheral neuropathy, and central nervous system effects. Specific fluoroquinolones may have slightly different side effect profiles. Always consult the prescribing information and a healthcare professional for a complete list and possible severity. | | alternatives | | | contraindications | Patients with known hypersensitivity to fluoroquinolones, or with certain pre-existing conditions (e.g., severe QT prolongation, severe myasthenia gravis) should not use fluoroquinolones. Consult the prescribing information and a healthcare professional. | | interactions | Fluoroquinolones may interact with certain medications, including antacids, other antibiotics, and medications affecting the cytochrome P450 system. Consult the prescribing information and a healthcare professional about any concurrent medications. | | warnings and precautions | Patients with pre-existing conditions (e.g., renal impairment, myasthenia gravis, cardiac conditions) should be monitored closely when taking fluoroquinolones. Patients should be cautioned about the potential for tendon rupture. Always consult the prescribing information and a healthcare professional. |
| | dosage | Dosage highly depends on the specific fluoroquinolone and the clinical situation. Consult the prescribing information for the *specific* fluoroquinolone, considering factors like the patient's age, renal function, and the severity of the infection. | | patient details | | | additional information | The information provided here is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for diagnosis, treatment, and any concerns regarding fluoroquinolones. |
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