name | Docusate Sodium Stool Softener |
classification | Bulk-forming laxative |
pharmacokinetics | Docusate sodium is a surfactant that promotes water and fat absorption into the stool. It works by increasing the surface area of the stool, making it softer and more easily passed. It is primarily absorbed in the small intestine. The exact pharmacokinetic properties in a specific individual can vary depending on factors including individual metabolism, drug interactions and the specific formulation of docusate sodium. Detailed pharmacokinetic data specific to a patient would require clinical assessment. |
suggested dosage | adult | 50 mg to 100 mg (1-2 tablets or capsules) orally 1-3 times per day, or as directed by a healthcare professional. Adjust dosage according to response. | specific dosage for patient 70kg | The provided general dosage information is appropriate but the dosage should be tailored by a healthcare professional to account for patient response. Individual responses and needs vary. A healthcare provider can best determine appropriate dosage for the individual. |
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indications | Relief of occasional constipation, preparation for bowel examinations (e.g., colonoscopy), and prevention of constipation associated with opioid use. |
safety in pregnancy | Available studies are not sufficiently conclusive to define a safety profile during pregnancy. Consult a healthcare provider before use during pregnancy. |
safety in breastfeeding | Docusate sodium is generally considered safe for use during breastfeeding, though individual cases should be evaluated by a healthcare provider. No definitive data exists regarding this. |
side effects | 1 | Nausea | 2 | Abdominal discomfort | 3 | Stomach cramps | 4 | Flatulence | 5 | Headache |
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alternatives | |
contraindications | 1 | Severe dehydration | 2 | Known hypersensitivity to docusate sodium or other ingredients | 3 | Obstruction of the intestines |
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interactions | 1 | Certain medications, such as digoxin and other drugs that may be affected by changes in electrolyte levels. | 2 | Other laxatives, including certain types of fiber supplements |
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warnings and precautions | 1 | Do not use for more than a few days without consulting a doctor if your constipation persists. | 2 | Do not use if you have severe abdominal pain, rectal bleeding, or other serious symptoms. These could indicate a more serious underlying condition and require immediate medical attention. | 3 | If your constipation is severe or persistent, consult a healthcare professional. | 4 | Use with caution in patients with underlying conditions such as liver or kidney disease, and consult your doctor before use. |
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additional information | Docusate sodium is a safe and commonly used medication, but it does not address the underlying cause of constipation. For chronic constipation, consult a healthcare professional to explore possible contributing factors and appropriate treatment strategies. |
patient details | |