| name | Coal Tar |
| classification | Keratolytic, antipruritic, antifungal |
| pharmacokinetics | Coal tar is largely absorbed into the skin and penetrates into hair follicles. Excretion is primarily via metabolism and excretion in the bile and urine. The precise pharmacokinetic profile depends on the specific formulation and route of application. Limited systemic absorption occurs. |
| suggested dosage | Dosage varies greatly depending on the condition being treated and the formulation. Coal tar preparations are typically applied topically to the affected skin, usually once or twice a day. Consult a dermatologist for specific dosage guidelines, as self-treatment is not recommended. |
| indications | Coal tar is primarily used to treat conditions such as psoriasis, seborrheic dermatitis, and other chronic skin conditions characterized by scaling and inflammation. It can improve symptoms by reducing inflammation, scaling, and itching. It can also help to reduce the proliferation of fungi. |
| safety in pregnancy | Limited data is available regarding the safety of coal tar during pregnancy. Due to the potential for systemic absorption, caution is advised. It is essential to discuss the use of coal tar with a healthcare provider before use during pregnancy. |
| safety in breastfeeding | Limited data exists regarding the safety of coal tar in breastfeeding women. Due to the possibility of systemic absorption, and potential transfer into breast milk, it is recommended to avoid use during breastfeeding, or consult a healthcare provider for guidance. |
| side effects | | 1 | Skin irritation (e.g., redness, burning, itching) | | 2 | Skin dryness and scaling | | 3 | Contact dermatitis | | 4 | Allergic reactions | | 5 | Hair discoloration and/or loss (with repeated applications) | | 6 | Rarely, systemic effects such as nausea, vomiting or neurological effects have been reported, but these are generally in cases of severe or improper use. |
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| alternatives | |
| contraindications | | 1 | Known allergy or sensitivity to coal tar | | 2 | Open wounds or skin lesions in the application area | | 3 | Infections (if coal tar is not used under the direction of a doctor) | | 4 | Severe skin conditions requiring a tailored treatment approach |
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| interactions | Limited interaction data is available. Potential interactions with other topical medications should be discussed with a healthcare provider, particularly if using other topical treatments simultaneously. Avoid mixing coal tar with other substances. |
| warnings and precautions | | 1 | Always apply a thin layer to the affected area. | | 2 | Avoid contact with eyes, mouth, and other mucous membranes. | | 3 | Monitor for signs of irritation, and discontinue use if significant irritation develops. | | 4 | Wash hands thoroughly after application. | | 5 | Patch testing may be useful to determine individual patient sensitivity. | | 6 | Patients should understand that improvement in symptoms may take several weeks. |
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| additional informations | Coal tar preparations come in various forms (creams, lotions, shampoos). The specific formulation and concentration should be determined in consultation with a healthcare professional, who can tailor the treatment to the individual's condition and needs. Do not use coal tar without the advice of a physician. |
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