| drug | Tinidazole |
| classification | Antiprotozoal, Antibacterial |
| pharmacokinetics | Tinidazole is rapidly absorbed following oral administration. Peak plasma concentrations are typically reached within 1-2 hours. It is extensively metabolized in the liver, primarily to inactive metabolites. The drug exhibits good tissue penetration into various organs and body fluids. Elimination occurs primarily through the liver and kidneys. The elimination half-life is typically 10-15 hours. |
| suggested dosage | The dosage of tinidazole varies depending on the indication. Consult a healthcare professional for appropriate dosage based on the specific condition being treated. A common dosage for some indications is 2 grams as a single dose or 500 mg twice daily for 3 to 5 days. The information provided here is for general knowledge and informational purposes only, and does not constitute medical advice. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not use this information to self-diagnose or self-treat. |
| indications | Tinidazole is used to treat infections caused by certain anaerobic bacteria and protozoa, including infections of the intestines (such as amoebiasis and giardiasis), vaginitis, and other infections. Specific conditions should be verified with a healthcare professional. |
| safety in pregnancy | Tinidazole is a pregnancy category C medication. Animal studies have shown adverse effects, and there are limited human studies available. The potential risks and benefits should be carefully considered by the patient and their physician before prescribing this medication during pregnancy. |
| safety in breastfeeding | It is not recommended to use tinidazole during breastfeeding. The drug may be excreted into breast milk and potential risks to the infant need to be evaluated carefully and weigh against the potential benefit to the mother. Consult a healthcare professional for personalized advice. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Headache | | 5 | Metallic taste | | 6 | Abdominal pain | | 7 | Loss of appetite | | 8 | Stomach upset | | 9 | Dry mouth | | 10 | Constipation | | 11 | Fatigue | | 12 | Dizziness | | 13 | Skin rash | | 14 | Allergic reactions |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity or allergy to tinidazole or any of its components. | | 2 | Severe liver disease. |
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| interactions | Tinidazole can interact with various medications, including those used to treat seizures, antidepressants, anticoagulants, and others. Always inform your healthcare provider about all medications you are currently taking. Specific interactions should be reviewed by the doctor. |
| warnings and precautions | | 1 | Monitor liver function tests if long-term use is considered. | | 2 | Avoid alcohol consumption during treatment and for at least 24-48 hours after the last dose. Alcohol can exacerbate certain side effects. | | 3 | Advise patients about the potential for disulfiram-like reactions with alcohol. | | 4 | Patient should be aware of the potential for severe allergic reactions. | | 5 | Patients with a history of blood disorders should be closely monitored for any adverse hematological effects. | | 6 | Caution in patients with a history of seizures or other neurological conditions. |
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| additional informations | Tinidazole should be taken as prescribed and patients should not adjust their own dosage. Patients should inform their doctor of any worsening symptoms or new side effects during therapy. |
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