| name | Tamsulosin (Flomax) |
| classification | Alpha-1A adrenergic receptor antagonist |
| pharmacokinetics | | absorption | Rapidly absorbed after oral administration, peak plasma concentrations typically achieved within 6 hours. | | distribution | Distributed widely throughout the body, with high concentration in the prostate. | | metabolism | Metabolized primarily in the liver, with a significant portion undergoing glucuronidation. | | excretion | Excreted primarily in the urine, mostly as metabolites. |
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| suggested dosage | | typical dosage | 0.4 mg once daily, taken orally, preferably at the same time each day. | | patient specific considerations | The dosage may be adjusted based on individual response and tolerability. Consult a doctor for personalized recommendations. The patient's age and weight are not the sole determinants for dosage; other factors such as renal function should be considered. |
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| indications | | 1 | Benign prostatic hyperplasia (BPH): Used to improve urinary flow and reduce symptoms associated with an enlarged prostate. | | 2 | Symptomatic relief of bladder outlet obstruction due to BPH. |
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| safety in pregnancy | Not recommended during pregnancy unless the potential benefit outweighs the potential risk. Limited data exists on use in pregnant women. Consult with your doctor to understand the risks and benefits in your individual situation. |
| safety in breastfeeding | Not recommended during breastfeeding. Tamsulosin can be secreted in breast milk, and its potential effects on the infant are not fully known. |
| side effects | | 1 | Dizziness | | 2 | Headache | | 3 | Lightheadedness | | 4 | Nasal congestion | | 5 | Postural hypotension (low blood pressure when standing up) | | 6 | Abnormal ejaculation (e.g., decreased volume or less frequent ejaculation) | | 7 | Abnormal vision (e.g., blurred vision) | | 8 | Fatigue | | 9 | Back pain | | 10 | Abdominal pain | | 11 | Nausea | | 12 | Vomiting | | 13 | Diarrhea | | 14 | Constipation | | 15 | Rash | | 16 | Pruritus | | 17 | Urinary tract infection | | 18 | Decreased libido |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to tamsulosin or other ingredients in the formulation. | | 2 | Severe hepatic impairment (liver dysfunction) | | 3 | Recent history of stroke or cerebrovascular accident | | 4 | Severe hypotension | | 5 | Severe renal failure |
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| interactions | | 1 | Certain medications, such as anticoagulants (blood thinners), can increase the risk of bleeding. Consult with a doctor about all medications you are currently taking. | | 2 | Antihypertensives and other medications affecting blood pressure may increase the risk of hypotension. |
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| warnings and precautions | | 1 | Patients with a history of orthostatic hypotension should be monitored carefully. | | 2 | Patients with pre-existing liver or kidney disease should be monitored carefully. Dosage adjustments may be needed. | | 3 | Avoid driving or operating machinery until the effects of the medication are known, especially after the initial dose or a dose increase. |
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| additional informations | | patient age and weight considerations | Age and weight are not primary factors in determining the dosage of Tamsulosin. Other factors like renal function, underlying conditions, and current medications must be considered to tailor the treatment to the patient. | | important notes | Always consult with a healthcare professional before starting or stopping any medication. Do not adjust dosages or stop taking the medication without consulting your doctor. |
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