name | Senna Laxative |
classification | Bulk-forming laxative, Stimulant laxative (specific formulation dependent) |
pharmacokinetics | Senna primarily stimulates colonic peristalsis. Poorly absorbed from the GI tract. Active metabolites form, acting mainly in the large intestine. Onset varies (6-12 hours for oral), duration also varies (12-24 hours). |
suggested dosage | adult 70kg | oral | general | Consult a healthcare professional for appropriate dose. Dosage varies by individual needs and formulation (e.g., Senna leaves, concentrate, glycosides). Do not exceed product packaging instructions. Use lowest effective dose for shortest duration possible to avoid dependence. | common start range | 15-30mg (active ingredient) orally once or twice daily. Refer to specific product labeling for exact dosage. |
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indications | Short-term relief of occasional constipation. Not for long-term use. |
safety in pregnancy | Limited data. Generally considered safe when used as directed, but consult a healthcare professional during pregnancy and breastfeeding for potential risks. |
safety in breastfeeding | Limited data. Possible minimal excretion into breast milk. Consult a healthcare professional. |
side effects | 1 | Abdominal cramping | 2 | Flatulence | 3 | Diarrhea | 4 | Nausea | 5 | Vomiting | 6 | Dehydration (with overuse/abuse) | 7 | Headache | 8 | Loss of appetite | 9 | Bloating |
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alternatives | |
contraindications | 1 | Severe dehydration | 2 | Intestinal obstruction/suspected blockage | 3 | Appendicitis | 4 | Allergy to Senna or components | 5 | Known sensitivity to stimulant laxatives | 6 | Colonic inflammation |
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interactions | Potential interactions with certain medications. Always inform your healthcare professional about all medications and supplements, including over-the-counter (OTC) products. |
warnings and precautions | 1 | Use cautiously in individuals with underlying cardiovascular or other medical conditions. | 2 | Do not use for prolonged periods without consulting a physician. | 3 | If symptoms persist or worsen, seek immediate medical attention. | 4 | Avoid use in cases of acute abdominal pain or severe pain. | 5 | Patients with a history of laxative abuse should consult their physician. |
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additional informations | Different Senna formulations exist with varying strengths and routes of administration. Consult a healthcare professional or pharmacist for the appropriate formulation. |
important disclaimer | This information is for general knowledge and informational purposes only, and does not constitute medical advice. Always consult a healthcare professional before starting any new medication, including laxatives. Self-treating with laxatives can be dangerous. Specific product labeling and instructions must be followed. |