| name | Retapamulin topical |
| classification | Antibiotic, Topical |
| pharmacokinetics | Retapamulin is a topical antibiotic primarily absorbed by the skin. Limited systemic absorption occurs, and metabolism occurs in the skin and liver. Peak concentrations in skin tissue are reached within a few hours of application. Elimination is primarily through metabolism and urinary excretion. The pharmacokinetic profile in a healthy 25-year-old male weighing 70kg is expected to be similar to other healthy adults. |
| dosage | Consult a physician for specific dosage based on infection severity and location. Typically, a thin film is applied to the affected area once daily. Treatment duration is determined by the physician based on clinical response, ranging from a few days to a few weeks. |
| indications | Retapamulin is primarily used to treat mild to moderate skin infections, most commonly caused by bacteria susceptible to the antibiotic. This includes impetigo (caused by *S. aureus* or *S. pyogenes*) and other superficial skin infections. Consult a physician for proper diagnosis and treatment recommendations. |
| pregnancy safety | Limited data exist. Use during pregnancy only if potential benefits outweigh risks to the fetus. Consult a physician. |
| breastfeeding safety | Limited data exist. Low levels are expected in breast milk, but effects on the infant are unknown. Consult a physician before use. |
| side effects | | 1 | Local reactions (irritation, redness, burning, itching, pain) at the application site are possible. | | 2 | Systemic side effects are rare due to limited absorption. | | 3 | Rare but possible serious adverse reactions (e.g., rash, swelling, difficulty breathing). Seek immediate medical attention. | | 4 | Contact dermatitis in some cases. |
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| alternatives | |
| contraindications | Hypersensitivity/allergy to retapamulin or its components. Avoid contact with eyes. Do not use on deep wounds where topical treatment may not be sufficient. |
| interactions | Limited interaction data. Consult a physician before use with other medications, including other topical medications. |
| warnings and precautions | | 1 | Apply only as directed, to the affected area. | | 2 | Avoid open wounds and deep lesions. | | 3 | Avoid contact with eyes. | | 4 | If symptoms worsen, don't improve, or new symptoms develop, seek immediate medical attention. |
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| additional information | Retapamulin is generally well-tolerated. Specific dosage depends on the extent and type of infection. |
| patient data | |
| disclaimer | This information is for general knowledge only and does not constitute medical advice. Always seek the advice of a medical professional for any questions about your particular circumstances. |
