| name | Phototherapy (UVB) |
| Classification | Phototherapy, topical; Photochemotherapy |
| Pharmacokinetics | UVB radiation penetrates the skin and triggers biological effects, primarily influencing immune responses and cellular processes. The precise pharmacokinetics are complex and not typically described in terms of absorption, distribution, metabolism, and excretion like traditional drugs. The effectiveness depends on factors like the intensity, duration, and wavelength of the UVB exposure. |
| suggested dosage | Dosage is highly individualized and depends on the specific condition being treated, the patient's skin type, and the intensity of the UVB lamp. A dermatologist will determine the appropriate dosage and schedule. This involves frequent monitoring and adjustments to avoid skin damage. |
| indications | | 1 | Psoriasis (plaque type) | | 2 | Psoriatic arthritis | | 3 | Vitiligo | | 4 | Atopic dermatitis | | 5 | Lichen planus | | 6 | Mycosis fungoides | | 7 | Other skin conditions responsive to phototherapy | | 8 | Other dermatologic conditions unresponsive to topical or systemic treatments |
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| safety in pregnancy | Limited data exists on the safety of UVB phototherapy during pregnancy. Although adverse effects are rare, it's generally not recommended without careful consideration by a dermatologist who is aware of the pregnancy. |
| safety in breast feeding | Limited data exists on the safety of UVB phototherapy while breast-feeding. It's generally recommended to avoid phototherapy during breastfeeding when possible and under the supervision of a dermatologist. However, there may be cases where the benefits outweigh the risks. |
| side effects | | 1 | Erythema (redness) | | 2 | Burning | | 3 | Pain | | 4 | Skin irritation | | 5 | Mild to moderate allergic reactions | | 6 | Increased risk of skin cancer (with long-term or high-dose exposure) | | 7 | Dry skin | | 8 | Peeling | | 9 | Blisters | | 10 | Tanning | | 11 | Acute reactions such as nausea, vomiting, or fever |
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| alternatives | |
| contraindications | | 1 | Skin cancer | | 2 | Photoallergic reactions | | 3 | Active infections of the skin | | 4 | Photosensitivity disorders | | 5 | Pregnancy (unless carefully weighed against potential benefits) | | 6 | Severe kidney or liver disease | | 7 | Immunosuppressed conditions (e.g., HIV, organ transplant recipients) | | 8 | Use with caution in patients with certain cardiac conditions or bleeding disorders. |
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| interactions | Concurrent use of certain medications or supplements may affect the effectiveness or safety of phototherapy. It's crucial to inform the prescribing dermatologist of all medications, supplements, and herbal remedies being used. |
| warnings | | 1 | UVB phototherapy must be performed under the careful supervision of a dermatologist or other appropriately trained healthcare professional. | | 2 | Patients must be monitored closely for adverse effects during and after each treatment. | | 3 | Patients should use high-SPF sunscreens when outside during and after treatment sessions. | | 4 | Skin cancer is a potential long-term side effect of prolonged and intensive phototherapy. |
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| precautions | | 1 | Monitor for signs of sunburn and/or skin damage. | | 2 | Avoid exposure to excessive sunlight during treatment. | | 3 | Follow the prescribed schedule for treatments carefully. | | 4 | Regular follow-up appointments with the dermatologist are crucial for monitoring and adjustments to the treatment regimen. |
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| additional informations | Phototherapy (UVB) is a complex therapy. Individualized treatment plans are essential for optimal results. Factors to consider include the severity of the condition, the patient's skin type, and the potential side effects. |
| patient profile | |
