| name | Biocompatible Bone Grafting Materials |
| Classification | Surgical materials, Biomaterials |
| Pharmacokinetics | Not applicable. Biocompatible materials are not absorbed or metabolized; they remain in the body as a graft or scaffold. |
| suggested dosage | Dosage is highly variable and depends on the specific material, the surgical procedure, the patient's needs, and the site of application. **It is crucial to consult with a surgeon and a qualified medical professional for the appropriate amount and type of biomaterial.** |
| indications | | 1 | Bone defects (following trauma, tumor resection, non-unions) | | 2 | Dental applications (implant support, bone augmentation) | | 3 | Craniofacial reconstruction | | 4 | Orthopedic procedures (fracture repair, joint reconstruction) | | 5 | Spine fusion | | 6 | Maxillofacial surgery |
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| Safety in pregnancy | Limited data on the use of some biocompatible materials during pregnancy. Specific recommendations depend on the material and the stage of pregnancy. **Consult with an obstetrician and a qualified medical professional.** |
| Safety in breastfeeding | Limited data available. The safety of using some bone grafting materials while breastfeeding is not fully established. **Consult with a medical professional before use.** |
| side effects | | 1 | Infection (at the graft site) | | 2 | Inflammation (local or systemic) | | 3 | Swelling | | 4 | Pain | | 5 | Delayed bone healing (in rare cases) | | 6 | Formation of a fibrous capsule around the graft | | 7 | Allergies to certain components (e.g., bovine collagen in some materials) | | 8 | Graft resorption (in some cases) | | 9 | Non-union of the bone graft (in some cases) |
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| alternatives | |
| contraindications | | 1 | Active infection at the surgical site | | 2 | Uncontrolled systemic disease | | 3 | Patient allergies to components of certain biomaterials | | 4 | Lack of suitable bone defect or other indication |
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| interactions | Potential interactions are material-specific and complex. Interactions may occur with other drugs or medical procedures. Consult with the surgical team to identify possible interactions. |
| warnings and precautions | | 1 | Appropriate surgical technique is crucial for success | | 2 | Careful patient selection is essential | | 3 | Monitoring of the graft site is important to identify potential complications | | 4 | Proper disinfection and sterile techniques during surgery are mandatory | | 5 | Long-term efficacy and safety of some materials are still under investigation |
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| additional informations | | 1 | Material properties (biocompatibility, strength, degradation rate, porosity) influence outcome | | 2 | Patient age and health status affect the suitability of biomaterials | | 3 | Bone grafting materials come in different forms (e.g., granules, blocks, membranes). | | 4 | Cost and availability of materials vary depending on the type | | 5 | The type of biomaterial chosen will depend on the nature of the bone defect, patient health conditions and other specific clinical factors. |
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| patient details | |
