| name | Autogenous Bone Graft |
| Classification | Surgical Technique/Biomaterial |
| Pharmacokinetics | Not applicable. Autogenous bone graft is not a drug, but a biological material. There is no absorption, distribution, metabolism, or excretion as with pharmaceutical drugs. |
| suggested dosage | Not applicable. The amount of bone graft used is determined by the specific surgical procedure and the amount of bone defect to be filled. |
| indications | | 1 | Fracture repair (especially in non-unions) | | 2 | Dental procedures (e.g., implants) | | 3 | Craniofacial reconstruction | | 4 | Spine fusion | | 5 | Bone defects due to trauma or disease | | 6 | Reconstruction of jaw and facial bones |
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| Safety in pregnancy | Limited data available. Autogenous bone grafting is not considered inherently unsafe during pregnancy. However, any surgical intervention should be carefully considered in pregnant patients, weighing potential risks against the benefit. |
| Safety in breastfeeding | Limited data available. Autogenous bone grafting is not considered to have direct effects on breastfeeding, but the surgical procedure itself should be assessed for potential effects on the mother and the infant. |
| side effects | | 1 | Infection (rare) | | 2 | Bleeding (potentially serious) | | 3 | Pain | | 4 | Swelling | | 5 | Numbness or paresthesia | | 6 | Bruising | | 7 | Delayed healing | | 8 | Graft resorption | | 9 | Implant failure (for dental applications) |
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| alternatives | |
| contraindications | | 1 | Active infection at the site of the graft | | 2 | Uncontrolled bleeding disorder | | 3 | Inability to tolerate general anesthesia | | 4 | Impaired immune response | | 5 | Poor bone quality at the recipient site |
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| interactions | No direct drug interactions. Interactions may exist with other surgical or medical interventions that impact wound healing or immune response. |
| warnings and precautions | | 1 | Careful surgical technique and meticulous wound management are critical to minimize complications. | | 2 | Careful patient selection and assessment of bone quality and blood supply are crucial for successful grafting. | | 3 | Potential for rejection, although less likely than with allograft bone | | 4 | Monitor for signs of infection, bleeding, and delayed healing. | | 5 | Inform the patient about potential risks and benefits before the procedure. | | 6 | Proper assessment of donor site is essential |
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| additional informations | | 1 | Autogenous bone grafting uses the patient's own bone, reducing the risk of rejection compared to allografts. | | 2 | Donor site morbidity is a possible consequence which must be weighed carefully against the potential benefits. | | 3 | The source of the bone may vary (e.g., iliac crest, rib, or tibia). | | 4 | Proper surgical technique is critical to ensure graft integration and long-term functionality. | | 5 | Patient age and general health are important factors to consider. |
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| patient information | |
