| name | Amoxicillin |
| Classification | Penicillins, Antibiotics |
| Pharmacokinetics | Amoxicillin is rapidly absorbed from the gastrointestinal tract. Peak serum concentrations are achieved within 1-2 hours after oral administration. It is distributed throughout the body, including the tissues and fluids. Amoxicillin is primarily excreted in the urine, mostly as the unchanged drug. The half-life of amoxicillin varies depending on the dose and route of administration but generally ranges from 1 to 2 hours. |
| suggested dosage | | adult | | oral | | 1 | | dose | 250 mg | | frequency | every 8 hours | | duration | until symptoms resolve |
| | 2 | | dose | 500 mg | | frequency | every 8 hours | | duration | until symptoms resolve |
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| | notes | Dosage may vary depending on the severity of infection and individual patient response. Always consult a healthcare professional for personalized dosage recommendations. Also, consider whether an extended-release or immediate-release formulation is needed based on the specific clinical situation. |
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| indications | | 1 | Bacterial infections of the respiratory tract (e.g., pneumonia, bronchitis) | | 2 | Bacterial infections of the urinary tract | | 3 | Bacterial infections of the skin and soft tissues | | 4 | Bacterial infections of the ear | | 5 | Bacterial infections of the gastrointestinal tract |
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| Safety in pregnancy | Amoxicillin is generally considered safe for use during pregnancy. However, it is important to discuss the use of any medication with a healthcare professional during pregnancy to ensure the safety for both the mother and the baby. Consult your doctor. |
| Safety in breastfeeding | Amoxicillin passes into breast milk in small amounts. In general, it is considered safe for use during breastfeeding, but again, consult your doctor. |
| side effects | | 1 | Nausea | | 2 | Vomiting | | 3 | Diarrhea | | 4 | Abdominal pain | | 5 | Headache | | 6 | Skin rash | | 7 | Allergic reactions (potentially severe) | | 8 | Superinfection (with yeast or other organisms) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to penicillins or cephalosporins | | 2 | Severe kidney disease |
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| interactions | | 1 | Certain antibiotics (e.g., Probenecid) | | 2 | Some medications for blood pressure | | 3 | Oral contraceptives (may decrease their effectiveness) |
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| warnings and precautions | | 1 | Monitor for signs of allergic reactions, particularly skin rashes or difficulty breathing. | | 2 | Monitor for signs of superinfection (e.g., vaginal yeast infections or oral thrush). | | 3 | Avoid use in patients with a history of severe allergic reaction to penicillins. | | 4 | Adjust dosage in patients with impaired kidney function. |
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| additional information | | patient age | 25 years | | patient weight | 70 kg | | important note | This information is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment. |
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