name | Nizatidine |
classification | H2-receptor antagonist |
pharmacokinetics | Nizatidine is rapidly absorbed after oral administration. Peak plasma concentrations are reached within 1-2 hours. The drug is extensively metabolized in the liver. The primary metabolites are inactive. The elimination half-life is approximately 2 hours. The drug is primarily excreted in the urine. |
suggested dosage | adult | Typically 150 mg twice daily. Dosage may be adjusted based on individual patient response and clinical condition. |
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indications | 1 | Peptic ulcer disease (prevention and treatment) | 2 | Gastroesophageal reflux disease (GERD) | 3 | Symptomatic relief of heartburn and acid indigestion |
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safety in pregnancy | Generally considered safe during pregnancy. Consult a healthcare professional for personalized advice. |
safety in breastfeeding | Limited data available. Consult a healthcare professional before use. |
side effects | 1 | Headache | 2 | Dizziness | 3 | Diarrhea | 4 | Constipation | 5 | Nausea | 6 | Vomiting | 7 | Abdominal pain | 8 | Skin rash | 9 | Pruritus | 10 | Gastrointestinal upset | 11 | Rarely, severe liver problems |
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alternatives | |
contraindications | 1 | Known hypersensitivity to Nizatidine or other H2 receptor antagonists | 2 | Severe hepatic impairment |
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interactions | 1 | Potential interactions with drugs metabolized by the liver (e.g., some antidepressants, oral anticoagulants). Consult a healthcare professional for specific interactions. | 2 | Alcohol consumption may increase the risk of side effects. |
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warnings and precautions | 1 | Use with caution in patients with renal impairment. | 2 | Monitor liver function tests periodically, especially in high-risk patients. | 3 | Closely monitor patients with a history of allergic reactions. |
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additional information | 1 | Available in tablets and suspensions. | 2 | Take as directed by a healthcare professional. | 3 | This information is for general knowledge only and does not constitute medical advice. Consult a healthcare professional before taking Nizatidine or any other medication. |
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patient information | age | 25 years | weight | 70 kg | notes | Patient data provided for informational purposes only. This data should not be used to substitute professional medical advice. |
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