| name | Mupirocin Topical |
| Classification | Antibacterial Topical |
| Pharmacokinetics | Mupirocin is a topical antibiotic that is not significantly absorbed systemically. The drug acts locally on the skin. It is primarily eliminated by metabolism and excretion in the urine. No significant accumulation occurs. |
| suggested dosage | Apply a thin film of mupirocin ointment or cream to the affected area 2 to 3 times daily for 2 to 5 days, or as directed by a physician. The duration of treatment may vary depending on the severity of the infection. |
| indications | Used to treat superficial skin infections caused by susceptible strains of Gram-positive bacteria, such as Staphylococcus aureus and Streptococcus pyogenes. Common uses include impetigo, folliculitis, and other skin infections. |
| Safety in pregnancy | Limited data is available on mupirocin use in pregnancy. While it is generally considered safe during pregnancy, use during pregnancy or breastfeeding should only be done as determined by a healthcare professional, especially during the first trimester. |
| Safety in breastfeeding | Mupirocin is considered safe for use in breastfeeding mothers. However, use should be as directed by a healthcare professional, and care should be taken to avoid application on the nipple or areola, if possible, to prevent possible local irritation to the baby. Limited information is available, thus clinical judgment of the practitioner is important. |
| side effects | | 1 | Local skin irritation (e.g., redness, itching, burning, rash) | | 2 | Pain at the application site | | 3 | Rare cases of allergic reactions (e.g., hives, skin rash) | | 4 | Contact dermatitis (in some cases) |
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| alternatives | |
| contraindications | | 1 | Known allergy or hypersensitivity to mupirocin or other related drugs | | 2 | Use in individuals with a history of contact dermatitis or skin sensitivities to similar topical medications. |
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| interactions | No significant drug interactions are known when using mupirocin topically. However, patients should inform their healthcare provider about all medications, supplements, and other substances they are taking, especially if they have any pre-existing conditions. |
| warnings and precautions | | 1 | Do not use on broken or damaged skin. | | 2 | Avoid contact with eyes, nose, or mouth. | | 3 | Ensure proper hygiene when applying the medication to prevent cross-contamination. | | 4 | If symptoms worsen or do not improve, seek medical advice. | | 5 | Proper hand hygiene is crucial before and after application. | | 6 | Use only as directed by a healthcare professional. |
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| additional information | Patients should be advised that mupirocin may stain clothing. Proper storage of the medication is important, as instructed on the packaging. The product should be stored at room temperature. |
| patient specific considerations | | age | 25 | | weight | 70 kg | | gender | male | | notes | The information provided is for general knowledge and informational purposes only, and does not constitute medical advice. It is essential to consult with a healthcare professional for any health concerns or before starting any new medication. |
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