| name | Mometasone Formoterol |
| classification | Combination inhaled corticosteroid and long-acting beta2-agonist (ICS/LABA) for the management of chronic obstructive pulmonary disease (COPD) and asthma. |
| pharmacokinetics | Mometasone furoate is a corticosteroid absorbed locally in the lungs. Formoterol is a long-acting beta2-agonist, primarily affecting the airways. The combination aims for a synergistic effect by combining the anti-inflammatory actions of the corticosteroid with the bronchodilating effects of the beta2-agonist. Specific pharmacokinetic data for the combined product may vary from the individual components. |
| suggested dosage | Dosage depends on the specific product and patient condition. Follow the prescription provided by a healthcare professional. Typical starting doses are on the medication packaging and patient information sheets. Adjust doses based on patient response and respiratory function monitoring. |
| indications | Treatment of asthma, particularly for controller medication, and COPD. Useful when both anti-inflammatory and bronchodilating actions are needed. |
| safety in pregnancy | Limited data on safety during pregnancy. A healthcare provider must carefully assess potential risks and benefits. Some inhaled corticosteroids may pose risks in pregnancy. Use only if no safer alternative exists. |
| safety in breastfeeding | Limited data on safety in breastfeeding mothers. Discuss potential risks and benefits with a doctor. Corticosteroids can be excreted in breast milk, so close monitoring is recommended. |
| side effects | | 1 | Headache | | 2 | Cough | | 3 | Pharyngitis | | 4 | Nausea | | 5 | Oral fungal infections (thrush) | | 6 | Tremor | | 7 | Cardiovascular effects (e.g., increased heart rate, palpitations, angina) | | 8 | Muscle pain | | 9 | Insomnia | | 10 | Anxiety | | 11 | Increased blood sugar (especially with long-term use) or effects on blood pressure |
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| alternatives | |
| contraindications | Hypersensitivity to mometasone, formoterol, or inactive ingredients. Avoid in patients with severe cardiovascular disease or uncontrolled hyperthyroidism. Use with caution in patients with a history of mental illness. |
| interactions | May interact with other medications, especially those for respiratory conditions or affecting the cardiovascular system. Consult a healthcare professional for potential interactions. |
| warnings and precautions | | 1 | Do not abruptly stop using; gradually reduce dose under medical supervision. | | 2 | Regular monitoring of lung function is essential. | | 3 | Advise patients on proper inhaler technique for optimal drug delivery and minimized side effects. | | 4 | Use cautiously in patients with pre-existing cardiovascular conditions, as increased heart rate and other cardiovascular effects have been observed. | | 5 | Monitor blood glucose levels, especially in diabetic patients, during long-term use. | | 6 | Oral fungal infections (thrush) are common; rinse mouth thoroughly after use. | | 7 | Proper inhaler storage and handling are critical to avoid contamination and maintain effectiveness. |
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| additional information | Patient age (25) and weight (70kg) are factors, but not determinants, in dose and safety considerations. Dosage should be individualized by a physician. Close monitoring is essential to assess response and manage potential side effects. |
