| name | Fluticasone Salmeterol |
| classification | Combination inhaled corticosteroid and long-acting beta2-agonist (LABA) for asthma and COPD. |
| pharmacokinetics | Fluticasone is absorbed in the lungs, metabolized primarily in the liver, and excreted in the urine and feces. Salmeterol is absorbed in the lungs, metabolized in the liver and excreted in the urine and feces. Specific pharmacokinetic parameters may vary by individual due to factors such as hepatic function and lung disease severity. |
| suggested dosage | Dosage is determined by individual need and disease severity. Consult a physician for specific dosage recommendations. General guideline examples for adult asthma patient, not a substitute for personalized medical advice. |
| indications | Treatment of asthma and chronic obstructive pulmonary disease (COPD). |
| safety in pregnancy | Limited data. Use with caution, and only if the potential benefit outweighs the potential risk to the fetus. Consult with your physician. |
| safety in breastfeeding | Limited data available, but it is possible that the drug may be present in breast milk. Consult with your physician. |
| side effects | | 1 | Headache | | 2 | Cough | | 3 | Throat irritation | | 4 | Hoarseness | | 5 | Nausea | | 6 | Vomiting | | 7 | Upper respiratory tract infection | | 8 | Oral fungal infections (thrush) | | 9 | Muscle tremor | | 10 | Insomnia | | 11 | Anxiety | | 12 | Hypertension | | 13 | Increased blood sugar (risk of diabetes) | | 14 | Fatigue | | 15 | Skin reactions (rash, itching) | | 16 | Cardiac arrythmias | | 17 | Increased heart rate | | 18 | Decrease in bone mineral density (with prolonged use) |
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| alternatives | |
| contraindications | | 1 | Known hypersensitivity to fluticasone or salmeterol or other components of the drug | | 2 | Severe uncontrolled infections (e.g. tuberculosis) |
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| interactions | | 1 | Other medications affecting pulmonary function or cardiovascular function | | 2 | High doses of oral corticosteroids (potentially reducing the effectiveness of inhaled corticosteroids) | | 3 | Certain medications affecting liver function |
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| warnings and precautions | | 1 | Use cautiously in patients with pre-existing cardiovascular disease, glaucoma, or hyperthyroidism | | 2 | Do not use in patients with active serious infections (e.g., tuberculosis or fungal infections) | | 3 | Do not abruptly stop using this medication | | 4 | Patients with a history of psychosis or other mental health conditions should use this medication cautiously and under medical supervision | | 5 | Monitor blood glucose levels in patients at risk for diabetes or with pre-existing diabetes | | 6 | Patients at high risk for osteoporosis (eg. long-term use, concomitant use of other medications associated with osteoporosis) |
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| additional informations | Regular monitoring of lung function, blood pressure, and glucose levels may be necessary, especially during prolonged use. Never adjust dosage yourself without consulting your doctor. Proper inhaler technique is crucial for optimal drug delivery and minimizing side effects. |
| patient information | | age | 25 years | | weight | 70 kg | | additional notes | This information is intended for educational purposes only and should not be considered medical advice. Consult with a physician or other qualified healthcare provider for any questions about your health or treatment. The specific dosage and recommendations are tailored to the individual patient based on their medical history, current health conditions, and other factors. |
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