| name | Minoxidil |
| classification | Peripheral vasodilator, Antihypertensive, Topical hair growth promoter |
| pharmacokinetics | | absorption | Topical application results in variable absorption, with systemic absorption possible. Systemic absorption is generally lower with topical formulations compared to oral administration. | | distribution | Distributed throughout the body, with potential for accumulation in tissues. | | metabolism | Primarily metabolized by the liver. Metabolism can vary depending on individual factors. | | excretion | Eliminated primarily through urine, with some excretion in the bile. |
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| suggested dosage | | topical hair growth | | description | Commonly applied twice daily. Specific concentrations and application frequency may vary based on the product. Consult with a dermatologist for specific recommendations. | | notes | Follow manufacturer instructions carefully. |
| | oral antihypertensive | | description | Dosage is highly individualized based on blood pressure response and patient tolerance. It is critical to follow the prescribing physician's instructions carefully. | | notes | Should not be self-administered; only for severe hypertension under medical supervision. |
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| indications | | topical hair growth | Treatment of androgenetic alopecia (male pattern baldness). | | oral antihypertensive | Treatment of severe, resistant hypertension. |
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| safety in pregnancy | | description | Limited data on use during pregnancy. Potential risks to the fetus are unknown. Should not be used during pregnancy unless clinically warranted and benefits outweigh risks. Consult with a healthcare professional. | | cautions | Minoxidil should be used only when absolutely necessary during pregnancy. |
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| safety in breastfeeding | | description | Limited data on use during breastfeeding. Potential for excretion into breast milk is unknown. Avoid use in lactating mothers. | | cautions | Safety concerns exist, and use during breastfeeding is not recommended. |
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| side effects | | 1 | Topical application: Skin irritation, redness, itching, dryness. Hair growth may be patchy. | | 2 | Systemic application (oral): Fluid retention (edema), dizziness, palpitations, headache, cardiac complications, and severe hypotension. | | 3 | Other: Possible changes in blood pressure and heart rate. |
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| alternatives | |
| contraindications | | 1 | Hypersensitivity to minoxidil or related compounds. | | 2 | Severe heart conditions (e.g., uncontrolled heart failure) | | 3 | Renal insufficiency | | 4 | Pregnancy (unless clinically necessary). | | 5 | Breastfeeding. |
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| interactions | | 1 | Concurrent use with other antihypertensive medications can result in additive hypotension. | | 2 | Concurrent use with certain medications may alter minoxidil's metabolism | | 3 | Consult a physician before using other medications concurrently. |
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| warnings and precautions | | 1 | Close monitoring of blood pressure and fluid balance is crucial, especially when used orally. | | 2 | Topical formulations may have variability in efficacy. Consult a dermatologist for specific application details. | | 3 | Do not use minoxidil in large quantities or frequently in the treatment of hair loss. Follow the instructions carefully. | | 4 | Patients with a history of cardiovascular disease, kidney disease or other medical problems should consult with a physician before taking minoxidil. |
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| additional informations | | important note | This information is for general knowledge only and should not be considered medical advice. Always consult a qualified healthcare professional for personalized medical advice, diagnosis, and treatment. | | for age weight | The dosage and use of minoxidil for a 25-year-old male weighing 70kg will differ based on the indication (hair growth or hypertension). Consultation with a physician is required. | | monitoring | Regular monitoring for blood pressure, fluid retention and other potential adverse effects is essential. |
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