| name | Long-Acting Reversible Contraceptives (LARCs) |
| classification | Contraceptives |
| Pharmacokinetics | LARCs vary in their pharmacokinetic profiles. For example, the intrauterine devices (IUDs) like the Copper T or hormonal IUDs, the levonorgestrel-releasing IUD, and implants (like Nexplanon) release hormones or copper ions directly into the uterus or surrounding tissues, influencing the local environment. The hormones, if present, affect the endometrium (uterine lining), cervical mucus, and ovulation process. Absorption, distribution, and elimination vary based on the specific LARC device and the individual. Generally, systemic absorption from the device is minimal, but localized effects are crucial. |
| suggested dosage | Dosage is not applicable in the same way as for oral medication. LARCs are devices and their effectiveness depends on proper placement and maintenance as per medical guidelines. Consult your healthcare provider for specific advice. |
| indications | | 1 | Prevent pregnancy | | 2 | Long-term contraception (up to 3-10 years depending on the specific device) | | 3 | Reduced frequency of hormonal fluctuations (compared to oral contraceptives) |
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| Safety in pregnancy | LARCs are not indicated if a pregnancy is confirmed. Immediate removal may be necessary if a pregnancy is suspected or confirmed. |
| Safety in breastfeeding | Most LARCs are generally considered safe during breastfeeding. Consult your doctor for specific advice. |
| side effects | | 1 | | effect | Irregular bleeding or spotting (especially initially) | | severity | Mild to moderate | | frequency | Common | | management | Monitor and may resolve with time. |
| | 2 | | effect | Pelvic pain or cramping | | severity | Mild | | frequency | Possible | | management | Consult your healthcare provider. |
| | 3 | | effect | Infection risk (with IUDs) | | severity | Low with proper insertion and care | | frequency | Possible but uncommon | | management | Follow physician's instructions regarding hygiene. |
| | 4 | | effect | Expulsion of the IUD | | severity | Potential for decreased effectiveness | | frequency | Possible | | management | Regular follow-up checkups. |
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| alternatives | |
| contraindications | | 1 | Known or suspected pregnancy | | 2 | Pelvic inflammatory disease | | 3 | Certain uterine abnormalities | | 4 | Allergy to components of the device (e.g., hormones, copper) |
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| interactions | Limited drug interactions are anticipated, but specific interactions must be considered with specific medical conditions. Consult your doctor. |
| warnings and precautions | | 1 | Proper placement and follow-up care are crucial for optimal effectiveness and safety | | 2 | Regular check-ups are essential to monitor device placement and evaluate its effectiveness. | | 3 | Consult your doctor about suitability for your individual needs and medical history. | | 4 | LARCs are not a protection against sexually transmitted infections. |
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| additional information | Different types of LARCs (hormonal IUDs, Copper IUDs, implants) have distinct benefits and drawbacks. Choosing the right method depends on individual factors. Consult your doctor for personalized recommendations. |
| patient profile | |
