name | Indapamide |
classification | Thiazide-like diuretic |
pharmacokinetics | absorption | Rapidly absorbed from the gastrointestinal tract. | distribution | Distributed throughout the body, including the kidneys and vascular system. | metabolism | Metabolized primarily in the liver. | excretion | Excreted primarily in the urine. |
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suggested dosage | adult | oral | initial dose | 2.5 mg once daily | maintenance dose | 2.5 mg to 10 mg once daily | max daily dose | 10 mg | special notes | The specific dosage and frequency may vary depending on individual patient response and the severity of the condition being treated. It's essential to follow the prescribed dosage regimen strictly and consult a healthcare professional for dosage adjustments. |
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indications | 1 | Essential hypertension | 2 | Congestive heart failure (in combination with other medications) |
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safety in pregnancy | category | C | description | Indapamide crosses the placenta and has been associated with potential fetal harm. It should be used during pregnancy only if the potential benefits outweigh the potential risks. Consult a healthcare professional for a thorough evaluation. |
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safety in breastfeeding | description | Indapamide is excreted in breast milk. The potential risks to the infant are not completely understood. Breastfeeding should be carefully considered, or interrupted if needed. Discuss this with your doctor. | recommendation | Breastfeeding is generally not advised with indapamide use due to potential infant side effects. |
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side effects | 1 | Headache | 2 | Dizziness | 3 | Fatigue | 4 | Nausea | 5 | Vomiting | 6 | Diarrhea | 7 | Dry mouth | 8 | Muscle cramps | 9 | Weakness | 10 | Decreased libido | 11 | Electrolyte imbalances (potassium and sodium) | 12 | Photosensitivity | 13 | Hypotension (low blood pressure) | 14 | Urinary frequency |
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alternatives | |
contraindications | 1 | Hypersensitivity to indapamide or other thiazide-like diuretics | 2 | Severe hepatic impairment | 3 | Severe renal impairment | 4 | Anuria |
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interactions | 1 | Lithium | 2 | Ciclosporin | 3 | Digoxin | 4 | Other antihypertensives | 5 | Nonsteroidal anti-inflammatory drugs (NSAIDs) | 6 | Potassium-sparing diuretics | 7 | Other drugs that affect electrolytes |
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warnings and precautions | 1 | Monitor blood pressure and electrolytes regularly | 2 | Use with caution in patients with gout, diabetes, or lupus | 3 | Consider kidney function before initiating treatment | 4 | Avoid excessive alcohol consumption while on the medication | 5 | May cause dehydration, particularly in hot weather |
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additional informations | 1 | Indapamide is a longer-acting diuretic than most other thiazides. | 2 | May cause hyperglycemia in susceptible patients | 3 | Indapamide is generally well-tolerated but some individuals may experience adverse effects. It's important to discuss these risks and benefits with your doctor. |
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patient specific info | age | 25 | weight | 70 | details | This information is for educational purposes only and does not constitute medical advice. It is essential to consult with a qualified healthcare provider before making any decisions about your medication regimen. |
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