| name | Erythromycin Topical |
| classification | Macrolide antibiotic |
| pharmacokinetics | Erythromycin topical preparations are primarily absorbed locally. Systemic absorption is minimal but can occur, especially with large areas of application or prolonged use. The extent of absorption is variable depending on formulation, vehicle, and skin condition. Metabolism is minimal. Excretion primarily through liver and kidneys. |
| dosage form | |
| dosage | Consult healthcare provider for specific dosage based on the affected area, condition, and formulation. Do not self-treat. |
| indications | | 1 | Treatment of mild to moderate skin infections caused by susceptible bacteria (e.g., impetigo, folliculitis, minor skin abrasions). | | 2 | Treatment of acne vulgaris when combined with other acne medications. | | 3 | Treatment of certain skin conditions like rosacea (not a primary indication). |
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| safety in pregnancy | Limited data. Generally considered safe for topical use on limited areas; minimal placental transfer expected. Consult a healthcare professional before use. |
| safety in breastfeeding | Likely safe due to minimal systemic absorption. Consult a healthcare professional for guidance. |
| side effects | | 1 | Local skin reactions (e.g., irritation, redness, itching). | | 2 | Allergic reactions (rare): rash, hives, difficulty breathing, swelling of face, lips, tongue, or throat. |
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| contraindications | | 1 | Known hypersensitivity to erythromycin or other macrolides. | | 2 | Severe skin conditions requiring systemic treatment. |
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| interactions | Limited interactions expected with topical use. Possible interactions with other topical medications; consult a healthcare provider. Systemic absorption may lead to interactions with other drugs (less likely with topical application). |
| warnings and precautions | | 1 | Do not apply to broken or infected skin. | | 2 | Discontinue use and contact a healthcare professional if skin reactions worsen or persist. | | 3 | Avoid contact with eyes. If contact occurs, flush thoroughly with water. | | 4 | If symptoms worsen or persist for more than a few days, discontinue use and consult a doctor. |
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| alternatives | |
| additional information | Erythromycin topical is not a substitute for oral antibiotics or other systemic treatments for severe infections. Proper hygiene and wound care are important adjuncts. This information is for educational purposes only; consult a healthcare professional for any health concerns or before making any decisions related to your health or treatment. |
